Bharat Book

Report On DNA Sequencing Equipment and Services Markets

Press Release   •   Oct 05, 2012 13:57 IST

This report, DNA Sequencing Equipment and Services Markets, represents the third time Kalorama has detailed the market for DNA sequencing systems, as well as consumables used in sequencing and sequencing services. Much has changed since the last Kalorama edition of this report. More companies are offering sequencing services. The market was moving in a relatively linear manner for about two years in terms of competition, with no disruptive technologies or business models introduced. After a period of relative stability, the market has seen major developments in 2011 and 2012. The introductions of the Ion Torrent PGM, PacBio RS and MiSeq have changed the situation in the market, with more new technologies expected from Ion Torrent as well as Oxford Nanopore. http://www.bharatbook.com/biotechnology-market-research-reports/dna-sequencing-equipment-and-services-markets.html
 
 DNA sequencing can be defined as any biochemical method for determining the order of the nucleotide bases, adenine, guanine, cytosine, and thymine, (A,G,C,T) in a DNA nucleotide. DNA Sequencing has accelerated research and discovery, which created a brisk market for sequencing systems that perform this work. TXThe growing availability of vast amounts of annotated sequence data permits life science researchers to undertake a much wider range of experiments.As part of the report’s coverage, the following data is provided: Business Report
 
 Current Market Estimate
 Historical Market Data since 2006
 Forecast to 2016
 Review of Major Company Sequencing Products
 The Status of Next Gen Systems
 Clinical Applications vs. Research Applications in Sequencing
 Litigation and Intellectual Property Developments
 Deals in the Industry
 Market Share of Major Players
 Challenges and Strategic Recommendations
 
 It is the beginning of a revolutionary time for the life sciences. Pricing changes, purchases by first-time users. Consortia, initiatives, a Groups have been organizing to sequence hundreds or thousands of individuals, species, tumors and the like in a short period of time – the 1,000 Genomes Project, the 1,001 Arabidopsis Project, and many others, many of which are covered in Chapter 2 – Trends. Longer-term, questions still remain for broad areas that are seen as large opportunities, such as disease prevention and diagnostics.
 
 The market remains volatile, but some patterns have been stabilizing in recent years. The report uses primary and secondary research to present market watchers with an assessment of the marketplace in 2012. As part of its coverage, the report profiles the following companies:
 
 454 Life Sciences (Roche)
 Complete Genomics
 Illumina
 Life Technologies
 Pacific Biosciences
 
 In the next five to ten years, the report details, any of the related areas could turn into home runs, or strikeouts, for sequencers and in general. The science is constantly evolving, and trends could work against DNA sequencers for some reason. Microarrays are still more cost-effective for GWAS, but given the trends in the science and the sequencing costs, it seems inevitable that will change. Further complicating things, somatic mutations, viral genome insertions, and epigenetic changes continue throughout life. The competition has been brutal as systems are constantly improved and new products are appearing with increasing frequency. Longer-term, new segments in diagnostics and industry are likely to open up further. The pharmaceutical industry is likely to be a growing segment, due to personalized medicine and other genomics-related projects.
 
 CHAPTER ONE: EXECUTIVE SUMMARY
 
Introduction
 New Systems, Services Create Uncertainty
 A Period of Rapid Adoption, But Lower Prices
 Further Longer-Term Challenges
 Rapid Growth Overall, But Intense Competition
 Customers’ Research Models Evolving
 Established Next-Generation Systems Seeing Slowdown
 Background
 Scope and Methodology
 Applications and Definitions
 Types of Samples
 DNA Sequencing Strategies
 
 CHAPTER TWO: SEQUENCER MARKET TRENDS
 
Industry and Technology Trends
 Market Fragmenting Into Multiple Product Types and Applications
 Continual Improvements Expand Sequencer Market
 Acquisitions and Collaborations for New Technologies
 Patent Infringement, Other Legal Disputes
 Slow Path to Potentially Large Clinical Markets
 Spread of Targeted Enrichment, Sequence-Capture Products and Services
 Synergies Appearing Between Life Science Companies’ Products
 Consumer Genomics, Genetic Testing, Pharmacogenetics Still Entering Mainstream
 NHGRI Funding, Budget, Periodic Strategic Planning
 NHGRI Shifts Funds from Centralized Sequencing Centers
 NHGRI White Paper #4: The Future of Genome Sequencing
 Genome Projects and Consortia
 The Cancer Genome Atlas (TCGA) Project
 National Plant Genome Initiative
 NSF/USDA Microbial Genome Sequencing Program
 
 CHAPTER THREE: DNA SEQUENCING SYSTEMS AND TECHNOLOGIES
 
454 Life Sciences (Roche)
 Genome Sequencer FLX, FLX+, Junior
 Illumina
 HiSeq, HiScan SQ, MiSeq, Genome Analyzer IIx
 Intelligent Biosystems (Qiagen)/Azco Biotech
 LI-COR Biosciences 4300
 Life Technologies/Applied Biosystems
 ABI Prism 310 Genetic Analyzer
 ABI Prism 3100-Avant Genetic Analyzer
 Applied Biosystems 3100 Genetic Analyzer
 Applied Biosystems 3130 Genetic Analyzer
 Applied Biosystems 3130xl Genetic Analyzer
 Applied Biosystems 3500 Genetic Analyzer
 Applied Biosystems 3730 DNA Analyzer
 Applied Biosystems 3730xl DNA Analyzer
 ABI SOLiD 4, 5500, 5500xl, 5500xl W Genetic Analyzers
 Ion Torrent Personal Genome Machine (PGM)
 Pacific Biosciences
 PacBio RS
 Technologies Under Development
 Introduction
 Human Microbiome Project Technology Development Awards
 
 CHAPTER FOUR: SEQUENCING MARKET ANALYSIS
 
Revenues Forecast
 Historical Revenues
 Overall Market Forecast
 Sequencing For a Clinical Purpose
 Roche
 ABI
 Illumina
 Affymetrix
 B.C. Cancer Agency
 Emory Genetics Lab
 Bacterial and Viral Applications for NGS
 eGenomics
 BGI
 Pacific Biosciences
 Clinical Sequencing vs. Research Sequencing Markets
 
 CHAPTER FIVE: COMPETITIVE ANALYSIS
 
Introduction
 Benchtop and Third-Generation Sequencers Bring Instability
 Second-, Third-Generation Battle Still Undefined, Unresolved
 Increased Flexibility with Purchasing
 ABI Capillary Electrophoresis Holds Onto Large Segment
 DNA Sequencer Market Shares
 Smaller Companies Experiencing Struggles
 Features and Strengths of Second-Generation Sequencers
 454 Life Sciences GS FLX–Strengths/Advantages
 454 Life Sciences GS FLX–Weaknesses/Disadvantages
 454 Life Sciences GS Junior–Strengths/Advantages
 454 Life Sciences GS Junior–Weaknesses/Disadvantages
 Applied Biosystems SOLiD–Strength/Advantages
 Applied Biosystems SOLiD–Weaknesses/Disadvantages
 Illumina HiSeq/HiScan SQ–Strength/Advantages
 Illumina HiSeq/HiScan SQ–Weaknesses/Disadvantages
 Illumina MiSeq - Strength/Advantages
 Illumina MiSeq-Weaknesses/Disadvantages
 Life Technologies PGM-Weaknesses/Disadvantages
 Pacific Biosciences PacBio RS-Strength/Advantages
 Pacific Biosciences PacBio RS-Weaknesses/Disadvantages
 
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DNA Sequencing Equipment and Services Markets
 
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