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Wegener Polyangiitis - Pipeline Review, H2 2015 Is Released

Press Release   •   Feb 04, 2016 14:50 IST

This report provides comprehensive information on the therapeutic development for Wegener Polyangiitis, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Wegener Polyangiitis and special features on late-stage and discontinued projects. Global Markets Directs report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Directs proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Directs team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease. Scope

The report provides a snapshot of the global therapeutic landscape of Wegener Polyangiitis - The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved in the therapeutics development for Wegener Polyangiitis and enlists all their major and minor projects - The report summarizes all the dormant and discontinued pipeline projects - A review of the Wegener Polyangiitis products under development by companies and universities/research institutes based on information derived from company and industry-specific sources - Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages - A detailed assessment of monotherapy and combination therapy pipeline projects - Coverage of the Wegener Polyangiitis pipeline on the basis of target, MoA, route of administration and molecule type - Latest news and deals relating related to pipeline products Reasons to buy - Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Develop strategic initiatives by understanding the focus areas of leading companies - Identify and understand important and diverse types of therapeutics under development for Wegener Polyangiitis - Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline - Devise corrective measures for pipeline projects by understanding Wegener Polyangiitis pipeline depth and focus of Indication therapeutics - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline

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Table of Contents

Table of Contents 2

List of Tables 5

List of Figures 5

Introduction 6

Global Markets Direct Report Coverage 6

Wegener Polyangiitis Overview 7

Therapeutics Development 8

Pipeline Products for Wegener Polyangiitis - Overview 8

Wegener Polyangiitis - Therapeutics under Development by Companies 9

Wegener Polyangiitis - Pipeline Products Glance 10

Late Stage Products 10

Clinical Stage Products 11

Early Stage Products 12

Unknown Stage Products 13

Wegener Polyangiitis - Products under Development by Companies 14

Wegener Polyangiitis - Companies Involved in Therapeutics Development 15

Bionovis SA 15

Bristol-Myers Squibb Company 16

ChemoCentryx, Inc. 17

Coherus BioSciences, Inc. 18

Epirus Biopharmaceuticals, Inc. 19

Genor BioPharma Co., Ltd. 20

GlaxoSmithKline Plc 21

Hospira, Inc. 22

Panacea Biotec Limited 23

Sandoz International GmbH 24

The International Biotechnology Center (IBC) Generium 25

Wegener Polyangiitis - Therapeutics Assessment 26

Assessment by Monotherapy Products 26

Assessment by Target 27

Assessment by Mechanism of Action 29

Assessment by Route of Administration 31

Assessment by Molecule Type 33

Drug Profiles 35

abatacept - Drug Profile 35

Product Description 35

Mechanism of Action 35

R&D Progress 35

belimumab - Drug Profile 38

Product Description 38

Mechanism of Action 38

R&D Progress 38

CCX-168 - Drug Profile 42

Product Description 42

Mechanism of Action 42

R&D Progress 42

rituximab biosimilar - Drug Profile 44

Product Description 44

Mechanism of Action 44

R&D Progress 44

rituximab biosimilar - Drug Profile 45

Product Description 45

Mechanism of Action 45

R&D Progress 45

rituximab biosimilar - Drug Profile 46

Product Description 46

Mechanism of Action 46

R&D Progress 46

rituximab biosimilar - Drug Profile 47

Product Description 47

Mechanism of Action 47

R&D Progress 47

rituximab biosimilar - Drug Profile 48

Product Description 48

Mechanism of Action 48

R&D Progress 48

rituximab biosimilar - Drug Profile 49

Product Description 49

Mechanism of Action 49

R&D Progress 49

rituximab biosimilar - Drug Profile 50

Product Description 50

Mechanism of Action 50

R&D Progress 50

rituximab biosimilar - Drug Profile 51

Product Description 51

Mechanism of Action 51

R&D Progress 51

rituximab biosimilar - Drug Profile 52

Product Description 52

Mechanism of Action 52

R&D Progress 52

Wegener Polyangiitis - Recent Pipeline Updates 53

Wegener Polyangiitis - Dormant Projects 62

Wegener Polyangiitis - Discontinued Products 63

Wegener Polyangiitis - Product Development Milestones 64

Featured News & Press Releases 64

Dec 04, 2014: ChemoCentryx Granted EU Orphan Drug Designation for CCX168, an Orally Administered Complement C5a Receptor Inhibitor, for the Treatment of Microscopic Polyangiitis and Granulomatosis With Polyangiitis, Two Forms of ANCA-Associated Vasculitis 64

Appendix 65

Methodology 65

Coverage 65

Secondary Research 65

Primary Research 65

Expert Panel Validation 65

Contact Us 65

Disclaimer 66" width="80" height="40" />Table of Contents

Table of Contents 2

List of Tables 5

List of Figures 5

Introduction 6

Global Markets Direct Report Coverage 6

Wegener Polyangiitis Overview 7

Therapeutics Development 8

Pipeline Products for Wegener Polyangiitis - Overview 8

Wegener Polyangiitis - Therapeutics under Development by Companies 9

Wegener Polyangiitis - Pipeline Products Glance 10

Late Stage Products 10

Clinical Stage Products 11

Early Stage Products 12

Unknown Stage Products 13

Wegener Polyangiitis - Products under Development by Companies 14

Wegener Polyangiitis - Companies Involved in Therapeutics Development 15

Bionovis SA 15

Bristol-Myers Squibb Company 16

ChemoCentryx, Inc. 17

Coherus BioSciences, Inc. 18

Epirus Biopharmaceuticals, Inc. 19

Genor BioPharma Co., Ltd. 20

GlaxoSmithKline Plc 21

Hospira, Inc. 22

Panacea Biotec Limited 23

Sandoz International GmbH 24

The International Biotechnology Center (IBC) Generium 25

Wegener Polyangiitis - Therapeutics Assessment 26

Assessment by Monotherapy Products 26

Assessment by Target 27

Assessment by Mechanism of Action 29

Assessment by Route of Administration 31

Assessment by Molecule Type 33

Drug Profiles 35

abatacept - Drug Profile 35

Product Description 35

Mechanism of Action 35

R&D Progress 35

belimumab - Drug Profile 38

Product Description 38

Mechanism of Action 38

R&D Progress 38

CCX-168 - Drug Profile 42

Product Description 42

Mechanism of Action 42

R&D Progress 42

rituximab biosimilar - Drug Profile 44

Product Description 44

Mechanism of Action 44

R&D Progress 44

rituximab biosimilar - Drug Profile 45

Product Description 45

Mechanism of Action 45

R&D Progress 45

rituximab biosimilar - Drug Profile 46

Product Description 46

Mechanism of Action 46

R&D Progress 46

rituximab biosimilar - Drug Profile 47

Product Description 47

Mechanism of Action 47

R&D Progress 47

rituximab biosimilar - Drug Profile 48

Product Description 48

Mechanism of Action 48

R&D Progress 48

rituximab biosimilar - Drug Profile 49

Product Description 49

Mechanism of Action 49

R&D Progress 49

rituximab biosimilar - Drug Profile 50

Product Description 50

Mechanism of Action 50

R&D Progress 50

rituximab biosimilar - Drug Profile 51

Product Description 51

Mechanism of Action 51

R&D Progress 51

rituximab biosimilar - Drug Profile 52

Product Description 52

Mechanism of Action 52

R&D Progress 52

Wegener Polyangiitis - Recent Pipeline Updates 53

Wegener Polyangiitis - Dormant Projects 62

Wegener Polyangiitis - Discontinued Products 63

Wegener Polyangiitis - Product Development Milestones 64

Featured News & Press Releases 64

Dec 04, 2014: ChemoCentryx Granted EU Orphan Drug Designation for CCX168, an Orally Administered Complement C5a Receptor Inhibitor, for the Treatment of Microscopic Polyangiitis and Granulomatosis With Polyangiitis, Two Forms of ANCA-Associated Vasculitis 64

Appendix 65

Methodology 65

Coverage 65

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