Denator AB

CDC invest in Denator’s unique heat stabilization technology

Press release   •   Jul 05, 2016 12:15 UTC

Uppsala, Sweden, June 28, 2016 – Denator, the Swedish-based biotechnology company specialized in biological sample preparation technologies announced today that the Center for Disease Control and Prevention (CDC), Atlanta, had made a major purchase of its proprietary heat stabilization technology Stabilizor™ T1. The Stabilizor system has been shown to inactivate pathogens in biological samples, including virus and bacteria, and is used by CDC to obtain high quality samples for advanced downstream analysis such as gene sequencing and mass spectrometry.

Stabilizor was originally developed for the preservation of biological samples. Heat stabilization using the Stabilizor system utilizes conductive heating to rapidly eliminate enzymatic degradation in tissue samples, and thus preserving their molecular composition. In collaboration with USAMRIID the possibility of utilizing the technique also for pathogen inactivation was investigated and successfully confirmed (Cazares, L. H. et al (2015). Heat fixation inactivates viral and bacterial pathogens and is compatible with downstream MALDI mass spectrometry tissue imaging. BMC microbiology, 15(1), 1.)

http://bmcmicrobiol.biomedcentral.com/articles/10.1186/s12866-015-0431-7

The CDC has been evaluating Stabilizor T1 over the last year and has now decided to invest in the technology. The growth of infectious diseases and the constant transformation of viral strains increase the need to analyze virus in a safe, standardized and convenient manner. Implementation of the Stabilizor system in laboratory workflows involving contaminated biological materials drastically increases the speed of sample handling and consistency of sample quality. Treated samples can then be handled outside bio safely level laboratories. An additional advantage is that the sample DNA remains intact.

“This is a significant and rewarding milestone for our heat stabilization technology” said Karsten Fjärstedt, CEO of Denator. “We are all aware of the escalating threat of virus and bacterial diseases, and are proud that our technology can enable researchers to inactivate pathogens in contaminated biological samples, and contribute to them learning more about these pathogens.”

ENDS


About Denator AB

Denator AB is a Swedish-based biotech company with a mission to enhance sample quality of biological samples and improve sample preparation in life science and clinical research markets. Based upon the company’s proprietary heat-stabilization technology, Denator develops and markets products that stabilize biological samples from the moment of sampling throughout the analytical workflow. This enables scientists to significantly enhance the quality of data obtained from analytical techniques used downstream.

Information about Denator is available at www.denator.com and information about Denator`s system to inactivate pathogens is available here http://denator.com/pathogen_inactivation

Stabilizor™ is a trademark of Denator AB.

Editorial Contact

Karsten Fjärstedt, CEO

Tel: +46 (0)705 106644

Email: karsten.fjarstedt@denator.com

Denator AB is a Swedish-based biotech company with a mission to enhance sample quality of biological samples and improve sample handling and preparation in life science and clinical research markets. The company’s proprietary heat stabilization technology is an additive-free preservation technology for biological samples which stops degradation and changes immediately and permanently. This ensures a stable sample from the moment of excision until the point of analysis which increases the accuracy and quality of analytical results.

For research use only. Not for use in diagnostic procedures.