2011-05-24 09:00 Attana Cell 200 - Bridging the gap between traditional biosensors and cell-based assays! Drug development is costly and risky and the need for technologies that accelerate the process of drug discovery becomes increasingly urgent. This paper shows four instances of how the Attana Cell 200 biosensor provides data enhancing the ability to select the right drug candidates earlier in the process.

2011-04-13 08:58 Attana has several Quartz Crystal Microbalance (QCM) based instruments and applications, all catering to crucial needs and developed in close collaboration with industry and universities. Examples include kinetic analysis on cell surfaces, candidate selection screening, aggregation characterization, epitope mapping and concentration determination of biopharmaceuticals.

2010-07-14 09:07 The objective of this application note was to determine off-rates of antibodies in mouse hybridoma supernatants and scaffold proteins in bacterial lysates using the Attana 200 system and Low Non-specific Binding (LNB) surfaces. Among other things, a method that can be used for clone selection, vaccine screening, biomarker discovery, biomanufacturing and performance studies was developed.

2010-06-30 09:58 The objective of this application note was primarily to screen mouse IgG antibodies from crude samples for dissociation rates of bound antigen, and to determine detailed kinetic rate constants between the antigen and an antibody selected in the screen. Among other things, a method to capture mouse IgG from hybridoma supernatants was developed which can be replicated for capture of human IgGs.

2010-01-13 19:02 Direct off-rate screening in Supernatants and Lysate

2009-07-06 14:19 A new system enables biomolecular interaction analyses to be performed on impure samples – thereby saving on time, labour and costs.