Pelago Bioscience AB grants Karo Bio AB license to the CETSA™ method

Pelago Bioscience AB and Karo Bio AB have today entered into a commercial license agreement and scientific collaboration regarding the use of the Cellular Thermal Shift Assay (CETSA^TM) for determination and quantification of drug–target interactions. Under the agreement, Pelago Bioscience grants Karo Bio a license to the CETSA method for use and applications within Karo Bio’s research & development. Pelago Bioscience will, through the agreement, and by access to Karo Bio’s expertise and knowledge, particularly with respect to the nuclear hormone receptor family, validate application of the CETSA method as relevant for the development of novel pharmaceuticals on this important drug target class. Other Terms and Conditions associated with the Agreement are undisclosed.

“We are excited about this opportunity to validate CETSA within this important target class and are proud to work with Karo Bio, who are such well renowned experts in the field’, says Michael Dabrowski CEO of Pelago Bioscience. ‘Karo Bio’s acquisition of a license to the CETSA method is a quality stamp and measure of the applicability and potential importance of CETSA in targeted drug discovery.”

Maria Sjöberg, VP and Head of Preclinical R&D at Karo Bio commented: “The CETSA method enables us to determine target engagement in relation to specific target classes and we believe that this will aid our development of novel therapies in the areas of autoimmune disease, inflammation and cancer. This combined license and collaborative agreement will enable us to employ the CETSA technology faster and more efficiently”