We are appealing for witnesses to a collision between a car and a motorcycle on the A27 Lewes Road between Polegate and Alfriston that occurred shortly after 7am.
Sadly the motorcyclist, a 37-year-old man from Chelmsford in Essex riding a white Honda CBR600, sustained fatal injuries and died at the scene. His next-of-kin have been informed.
The collision occurred just east of Wilmington crossroads and led to the A27 being closed in both directions. The road re-opened just before noon. The car driver invoilved, a 53- year-old man from Newhavenn in a blue Audi A4, was uninjured.
Sergeant Stacey Ellott, of the Surrey and Sussex roads policing unit, said: "The closure inevitably caused significant disruption to traffic and we would like to thank drivers who had to take alternative routes for their patience and understanding.
She added: "The circumstances are being fully investigated and so we would appreciate hearing from anyone who witnessed the collision, who may have dash-cam footage, or who noticed either vehicle being driven shortly before the collision occurred to get in touch."