Detectives are appealing for witnesses following a serious road traffic collision on the A12, near the Leytonstone junction.
Police were called at approximately 04:50hrs on Sunday 21 January to a vehicle having collided with a lampost.
Officers attended along with LAS and LFB.
The driver, a man in his 30s, was taken to an east London hospital where he remains in a critical condition.
His next of kin have been informed.
The car, a black Ford Focus, was travelling west bound along the A12, when it collided with the lampost.
No arrests have been made.
Anyone who witnessed or anyone with information about the collision is asked to call investigating officers from the Roads and Transport Policing Command on 020 8497 4874 or contact via Twitter @MetCC.