Detectives from the Roads and Transport Policing Command are appealing for information and witnesses following the death of a motorcyclist.
At 01:59hrs on Monday, 28 December, police were called to reports of a road traffic collision on the westbound A406 at Staples Corner.
Officers and London Ambulance Service attended and found a male motorcyclist suffering from critical injuries following a collision with a barrier.
The motorcyclist, aged in his fifties, was pronounced dead at the scene a short while later.
Next-of-kin have been informed, but formal identification awaits. A post-mortem examination will be held in due course.
At this early stage, it appears as though no other vehicle was involved in this incident. Enquiries are, however, ongoing.
Any witnesses or anyone with any information is asked to call the Serious Collision Investigation Unit at Alperton Police base 0208 9919555 or Crimestoppers anonymously on 0800 555 111.