The bone metabolism therapeutics market has been forecast to increase at a compound annual growth rate (CAGR) of 5.2% over the next five years, increasing from a value of $15 billion in 2010, to hit a market valuation of $27.1 billion by 2018.
Bone metabolism is a lifelong process where mature bone tissue is removed from the skeleton (a process called bone resorption) and new bone tissue is formed (a process called ossification or new bone formation).
These processes also control the reshaping or replacement of bone following injuries like fractures but also micro-damage, which occurs during normal activity. Remodelling responds also to functional demands of the mechanical loading.
The growth in the bone metabolism therapeutics market is mainly due to the contribution of osteoporosis market. The revenue of osteoporosis market alone has approximately 68% of the total bone metabolism revenue.
The cells responsible for bone metabolism are known as osteoblasts, which secrete new bone, and osteoclasts which break bone down. The structure of bones as well as adequate supply of calcium requires close cooperation between these two types of cells.
It relies on complex signalling pathways to achieve proper rates of growth and differentiation. These signalling pathways include the action of several hormones, including parathyroid hormone (PTH), vitamin D, growth hormone, steroids, and calcitonin, as well as several cytokines.
It is in this way that the body is able to maintain proper levels of calcium required for physiological processes.
For more information on the bone metabolism market, see the latest research: Bone Metabolism Market
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