The global Huntington's Disease Therapeutics market is projected to exceed US$870 million by 2018, driven by growing awareness about the disease worldwide, huge unmet patient needs, and developments in diagnosis and treatment efficacy.
Huntington's Disease (HD) is a disorder of the brain transmitted through autosomal dominant inheritance. The disease is one of the most common hereditary diseases. The global Huntington's Disease (HD) therapeutics market is vastly underserved with only one approved product, Xenazine®. Xenazine® is the only FDA approved pharmaceutical in the United States indicated for HD and prescribed for the treatment of chorea associated with the disease. Huntington's Disease is a relatively rare neurodegenerative disorder, and hence the price of Xenazine® is placed at a premium due to its 'orphan drug' status. The global market is forecast to witness significant growth attributed mainly to the high costs of this single existing approved therapy.
The absence of curative treatment options has led manufacturers to increase investment in R&D for quickly transforming their concepts into proprietary technologies and innovative solutions. Pipeline drugs with high patient compliance, improved safety, efficacy profiles, and affordability have an opportunity to achieve blockbuster status in the global market. Further, increasing numbers of pre- and post-symptomatic patients has further ignited the interests of market participants in conducting clinical research in the realm of HD therapeutics.
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