Diagnosed prevalent cases in the global type 2 diabetes market reached over186 million in 2012, with 154.94 million diagnosed prevalent cases in the US, India and China combined. Diagnosed prevalent cases of type 2 diabetes in the 10MM are expected to grow by 7.57% annually, reaching a total of 327.16 million cases by 2022.
It is projected that there will be a substantial increase in the prevalent cases of diagnosed type 2 diabetes in the 10MM. The number of prevalent type 2 diabetic cases is increasing around the world due to the actual increase in the incidence of type 2 diabetes, along with the change in population demographics in the respective markets. Furthermore, growth in prevalent cases is attributed to increased prevalence of risk factors associated with type 2 diabetes, such as obesity and physical inactivity, together with urbanization. Diabetes is undoubtedly one of the most challenging public health problems of the 21st century, with an increasing burden of the disease in all the markets and its strong association with cardiovascular morbidity and mortality.
Type 2 diabetes, formerly known as non-insulin dependent diabetes mellitus or adult-onset diabetes mellitus, is a chronic disorder of glucose equilibrium and results from the body's inability to make use of available insulin along with relative insulin deficiency (WHO, 2013). The condition is characterized by excess production of glucose by liver cells along with impaired insulin secretion which leads to an increased blood and urine glucose level. In addition, the disease leads to steady decline in the beta cells of the pancreas, mainly affecting the metabolism of muscle cells, liver cells and fat cells (Camacho et al., 2007). Type 2 diabetes constitutes approximately 90% of all diabetes cases around the world, with older age, family history of diabetes, obesity and physical inactivity being the major causes; type 1 diabetes and gestational diabetes constitute the remaining 10% of the cases (Camacho et al., 2007; CDC, 2011d; IDF, 2013).
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