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Protein engineering industry driven by the need for drugs with improved efficiency and specificity

Press release   •   Apr 10, 2013 09:51 BST

The protein engineering market has been forecast to increase at a compound annual growth rate (CAGR) of approximately 11% over the next five years, rising from a total of $100.1 billion in 2012, to hit a market value of $168 billion by 2017.

Protein engineering is the process of developing useful or valuable proteins. It is a young discipline, with much research taking place into the understanding of protein folding and recognition for protein design principles.

There are two general strategies for protein engineering, rational design and directed evolution. These techniques are not mutually exclusive; researchers will often apply both. In the future, more detailed knowledge of protein structure and function, as well as advancements in high-throughput technology, may greatly expand the capabilities of protein engineering.

Eventually, even unnatural amino acids may be incorporated thanks to a new method that allows the inclusion of novel amino acids in the genetic code.

The use of monoclonal antibodies in therapeutics such as oncology, auto immune and inflammatory diseases are expected to increase over the next five years, with China's growing interest in the research of monoclonal antibodies expected to increase market share further.

Proteins exhibit high specificity and less immunogenicity and are widely used as therapeutic agents in the treatment of various disorders and diseases. There are more than 200 protein-based products currently being marketed; 90% of them are used as therapeutics.

In order to improve their clinical potential, second generation recombinants are being developed, each exhibiting improved efficiency and potency depending on their applications.

The protein engineering market is driven by the need for drugs with improved efficiency and specificity, technological capabilities, rise of antibody based drugs, and steady growth in the therapeutic market.

With growing incidences of cancer, autoimmune disorders, and infectious disease, spurt of new opportunities for growth of the market is expected by the end of this decade.

For more information on the protein engineering market, see the latest research: Protein Engineering Market

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