Gene linked to higher stroke and heart attack risk - Stroke Association response

Researchers at Kings College London have identified a gene that may put people at greater risk of strokes and heart attacks.

The study's findings suggest that the gene fault may encourage the formation of blood clots - the ultimate cause of most heart attacks and strokes.

Developing a genetic test could help identify people at highest risk, allowing doctors to suggest more potent medication or lifestyle changes.

Dr Shamim Quadir, research commuivations manager at the Stroke Association, commented:“Findings from previous research investigating this genetic variant of a protein known as glycoprotein IIIa have been unclear. These latest results are an important step forward in stroke research. They suggest that people who possess this genetic variant known as PIA2 are at increased risk of stroke caused by a blood clot.

“However, even if you have a family history of stroke or have any other risk factors, this does not mean that the condition is inevitable. Regular exercise, eating a balanced diet and stopping smoking can be important steps to significantly reduce your stroke risk.

“We hope the findings from this study could lead to many more people who are most at risk of this devastating condition being identified. Understanding more about who is most at risk of stroke is essential in preventing as many strokes as possible in the future.”