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A new study shows that a novel imaging-based method for defining appropriateness of breast cancer treatment is as accurate as the current standard-of-care and could reduce the need for invasive tissue sampling. The results suggest that the method might lead to more optimal treatment of individual patients.
Most horses today are treasured for their ability to run, work, or be ridden, but have lost their wild-type camouflage: pale hair with zebra-like dark stripes and markings known as the Dun pattern. Now an international team of scientists has discovered what causes the Dun pattern and why it is lost in most horses.
Experiencing a traumatic event can cause life-long anxiety problems, called posttraumatic stress disorder. Swedish researchers from Uppsala University and Karolinska Institutet now show that people with posttraumatic stress disorder have an imbalance between two neurochemical systems in the brain, serotonin and substance P. The greater the imbalance, the more serious the symptoms patients have.
The press release "Posttraumatic stress disorder reveals an imbalance between signalling systems in the brain" is cancelled. Embargo until December 1st at 9.00 GMT
The ruff is a Eurasian shorebird that has a spectacular lekking behaviour where highly ornamented males compete for females. Now two groups report that males with alternative reproductive strategies carry a chromosomal rearrangement that has been maintained as a balanced genetic polymorphism for about 4 million years.
Many of the world’s approximately 117 million lakes act as wet chimneys releasing large amounts of the greenhouse gas carbon dioxide into the atmosphere. The most recent estimates show that CO2 emissions from the world’s lakes, water courses and reservoirs are equivalent to almost a quarter of all the carbon dioxide produced by burning fossil fuels.
In June, Uppsala Conflict Data Program (UCDP) reported that the number of fatalities in armed conflict has increased substantially in recent years, and that 2014 was the most violent year since the end of the Cold War. New data show that also the other two types of violence analyzed by the UCDP – conflict between non-state actors and violence targeting civilians – increased substantially in 2014.
One of the major global healthcare challenges today is the increasing prevalence of obesity and overweight caused by unhealthy diets. The steering committee of the Uppsala Health Summit has decided that this pressing issue is to be the focus of next year’s Uppsala Health Summit.
The aim of Uppsala Health Summit, this summer’s international summit about antibiotic resistance, was to make real progress in combatting this threat to public health. The conclusions have now been presented in a report which provides policy makers and medical professionals with a number of concrete recommendations.
By meticulously examining sediments in China’s Yellow River, a Swedish–Chinese research group are showing that the history of tectonic and climate evolution on Earth may need to be rewritten. Their findings are published today in the highly reputed journal Nature Communications.
1.Schematic human brain with hippocampus in white. 2.Cross section of hippocampus with pyramidal cells depicted with the major incoming fibres SC (schaffer collaterals, green), TA (temperoammonic pathway, blue), SH (septohippocampal pathway, black) 3.The gatekeeper (red) counteract signaling from TA pathway, thereby allowing local inputs from SC pathway on pyramidal cells to become stronger.