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New solar forecasting model performs best

New solar forecasting model performs best

Press releases   •   Jun 29, 2020 04:01 BST

A new mathematical model for predicting variations in solar irradiance has been developed at Uppsala University. It may help to promote more efficient use of electricity from solar energy. In tests of various data models, the model proved capable of making highly reliable forecasts, and emerged as the best for this purpose in some respects.

Novel function of platelets in tumour blood vessels found

Novel function of platelets in tumour blood vessels found

Press releases   •   Jun 25, 2020 08:03 BST

Scientists at Uppsala University have discovered a hitherto unknown function of blood platelets in cancer. In mouse models, these platelets have proved to help preserve the vascular barrier which makes blood-vessel walls selectively impermeable, thereby reducing the spread of tumour cells to other parts of the body. The study is published in the journal Cancer Research.

A vital game of hide-and-seek elucidated by novel single-molecule microscopy

Press releases   •   Jun 24, 2020 16:00 BST

Life depends on an intricate game of hide-and-seek taking place inside the cell. New research, which is now published in the journal Nature, sheds light on the mechanisms with which DNA-binding proteins search the genome for their specific binding sites.

Molecular simulations show how drugs block key receptors

Press releases   •   Jun 24, 2020 10:35 BST

Many pharmaceuticals work by targeting what are known as “G-protein-coupled receptors”. In a new study, scientists from Uppsala University describe how they have been able to predict how special molecules that can be used in new immunotherapy against cancer bind to these receptors.

Increasing levels of violence in Africa – peace researchers worried by recent trend

Press releases   •   Jun 15, 2020 07:30 BST

New data from the Uppsala Conflict Data Program (UCDP), Uppsala University, shows that the number of fatalities in organised violence continues to decrease. The declared defeat of Islamic State (IS) in Syria and Iraq has pushed the number of fatalities to its lowest level since the outbreak of the Syrian civil war in 2011. However, peace researchers are worried about recent trends in Africa.

Ancient enzymes can contribute to greener chemistry

Ancient enzymes can contribute to greener chemistry

Press releases   •   Jun 10, 2020 10:01 BST

A research team at Uppsala University has resurrected several billion-year-old enzymes and reprogrammed them to catalyse completely different chemical reactions than their modern versions can manage. The method can be used to develop sustainable solutions within biotechnology, such as for enzyme bioreactors or to chemically degrade environmental toxins.

​New method to identify genes that can drive development of brain tumours

​New method to identify genes that can drive development of brain tumours

Press releases   •   Jun 09, 2020 13:07 BST

Researchers at Uppsala University have developed a method for identifying functional mutations and their effect on genes relevant to the development of glioblastoma – a malignant brain tumour with a very poor prognosis. The study is published in Genome Biology.

Temperate insects as vulnerable to climate change as tropical species

Press releases   •   Jun 08, 2020 14:31 BST

In previous research, it has been assumed that insects in temperate regions would cope well with or even benefit from a warmer climate. Not so, according to researchers from the Universities of Uppsala and Lund in Sweden and Oviedo, Spain, in a new study. The earlier models failed to take into account the fact that insects in temperate habitats are inactive for much of the year.

DNA increases our understanding of contact between Stone Age cultures

DNA increases our understanding of contact between Stone Age cultures

Press releases   •   Jun 05, 2020 12:34 BST

What kind of interactions did the various Stone Age cultures have with one another? In a new interdisciplinary study, researchers have combined archaeological and genetic information to better understand Battle Axe cultural influences discovered in graves of the Pitted Ware culture. The findings are published in the American Journal of Physical Anthropology.

New test method can offer safer dosages of hydroxychloroquine

Press releases   •   Jun 01, 2020 01:00 BST

Researchers at Uppsala University and Uppsala University Hospital have developed a new method to measure levels of the medication hydroxychloroquine in patients with the rheumatic disease systemic lupus erythematosus (SLE). The analysis method may also be useful in other areas, such as in the treatment of COVID-19. The study is being published in Arthritis Research and Therapy.

Cold-adapted enzymes can transform at room temperature

Press releases   •   May 26, 2020 10:00 BST

Enzymes from cold-loving organisms that live at low temperatures, close to the freezing point of water, display highly distinctive properties. In a new study published in Nature Communications, scientists at Uppsala University have used large-scale computations to explain why many cold-adapted enzymes stop functioning at around room temperature.

Advanced X-ray technology tells us more about Ménière's disease

Advanced X-ray technology tells us more about Ménière's disease

Press releases   •   May 20, 2020 08:00 BST

The organ of balance in the inner ear is surrounded by the hardest bone in the body. Using synchrotron X-rays, researchers at Uppsala University have discovered a drainage system that may be assumed to play a major role in the onset of Ménière's disease, a common and troublesome disorder. These results are published in the journal Scientific Reports.

Carl Linnaeus’s household laid the foundation for his scientific work

Carl Linnaeus’s household laid the foundation for his scientific work

Press releases   •   May 20, 2020 07:00 BST

Without a wife and a well-functioning household, Carl Linnaeus would have had difficulty becoming the prominent scientist that he was. Mastering social codes, like clothing and hosting guests for dinners, was crucial for having a career in the 18th century. These are the conclusions of a recently defended thesis at Uppsala University.

​Treatment no better in clinical trials

​Treatment no better in clinical trials

Press releases   •   May 11, 2020 10:51 BST

Patients taking part in clinical trials do not receive better treatment than other patients. This is the conclusion of a new study led from Uppsala University and published in peer-reviewed journal BMC Cancer, which confirms the results of an earlier study from 2004.

How gene flow between species influences the evolution of Darwin’s finches

How gene flow between species influences the evolution of Darwin’s finches

Press releases   •   May 04, 2020 15:42 BST

Despite the traditional view that species do not exchange genes by hybridisation, recent studies show that gene flow between closely related species is more common than previously thought. A team of scientists from Uppsala University and Princeton University now reports how gene flow between two species of Darwin’s finches has affected their beak morphology.

AI - a New Tool for Cardiac Diagnostics

Press releases   •   May 04, 2020 13:24 BST

Artificial intelligence (AI) may be an aid to interpreting ECG results, helping healthcare staff to diagnose diseases that affect the heart. Researchers at Uppsala University and heart specialists in Brazil have developed an AI that automatically diagnoses atrial fibrillation and five other common ECG abnormalities just as well as a cardiologist.

Lymphatic vessels in mice and humans: alike yet different

Press releases   •   May 04, 2020 12:23 BST

In an international collaboration, researchers from Uppsala University have mapped the lymph node lymphatic vessels in mice and humans down to the level of individual cells. The results may eventually help scientists to discover new methods for strengthening the immune system against viruses and cancer. Their work has been published in the journal Frontiers of Cardiovascular Research.

Large differences in personality traits between patients with social anxiety disorder

Large differences in personality traits between patients with social anxiety disorder

Press releases   •   Apr 29, 2020 19:00 BST

Individuals with social anxiety disorder have markedly different personality traits than others. Emotional instability and introversion are hallmarks, according to a new study from Uppsala University published in PLOS ONE.

New study takes the pulse of a sleeping supervolcano

New study takes the pulse of a sleeping supervolcano

Press releases   •   Apr 23, 2020 13:09 BST

Under the volcanoes in the Central Andes there is a gigantic reservoir of molten magma. For several million years, it has been there without fully solidifying or causing a supervolcanic eruption. Geologists have long wondered how this is possible. Researchers from Uppsala University, among others, have now discovered that the secret may be hidden tributaries of hot magma from inside the Earth.

Type 2 diabetes: Too much glucagon when α-cells become insulin resistant

Press releases   •   Apr 20, 2020 14:35 BST

Patients with type 2 diabetes secrete not only too little insulin but also too much glucagon, which contributes to poor blood glucose control. A new study from Uppsala University suggests that this is because the glucagon-secreting α-cells have become resistant to insulin.