Perfusion is the passage of fluid through the lymphatic system or circulatory system to a tissue or an organ, generally indicating to the delivery of blood to a capillary bed in the tissue. Human body tissues require adequate blood supply to function normally. Weak perfusion may lead to diseases such as deep vein thrombosis. It is important to maintain perfusion during surgeries, primarily cardiothoracic surgery.
Expansion of the global perfusion systems market is due to the increasing number of surgeries related to cardiothoracic diseases and increased initiatives by NGOs and governments to inspire organ donation. The high cost of organ transplantation as well as the ever rising supply-demand gap of organs are anticipated to restrain the global perfusion systems market. The launch of technologically advanced products for the purpose of improved efficiency and cost-effectiveness is estimated to create opportunities for the global perfusion systems market. For example, adoption of portable organ perfusion systems is likely to increase during the forecast period due to associated benefits with its usage such as cost-efficiency, ease of access, and portability.
In terms of product type, the perfusion systems can be segmented into cardiopulmonary perfusion systems, cell perfusion systems, and ex vivo organ perfusion systems. The cardiopulmonary perfusion systems segment can be further sub-segmented into perfusion pumps, heart-lung machines, oxygenators, cannulas, monitoring systems, and others. The oxygenators segment contributes significantly to the cardiopulmonary perfusion systems segment. The ex vivo organ perfusion systems can be further sub-segmented into normothermic machine perfusion and hypothermic machine perfusion. The cell perfusion systems segment can be further sub-segmented into microfluidic perfusion systems, bioreactor perfusion systems, small-mammal organ perfusion systems, and gravity or pressure-driven perfusion systems. The bioreactor perfusion systems segment is anticipated to hold a prominent share in the cell perfusion systems segment of the market.
In terms of end-user, the global perfusion systems market can be segmented into hospitals, ambulatory surgical centers, clinics, and others. The ambulatory surgical centers and hospitals segments are estimated to hold major share, of the market due to rise in number of cardiothoracic surgeries and increasing number of organ transplantations.
In terms of geography, the global perfusion systems market can be segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America holds a prominent share of the global perfusion systems, followed by Europe and Asia Pacific. The market in Asia Pacific is anticipated to expand significantly during the forecast period, primarily due to rising organ donations and transplants, increasing geriatric population in Japan, and expansion of the pharmaceutical and biotechnology R&D industries in China. Existence of initiatives from nonprofit organizations such as Donate Life America in the U.S. and government initiatives such as National Organ Transplant Program in India are fueling the market.
Extensive R&D for development of innovative perfusion techniques is on priority by top market players. For example, TransMedics, Inc. carried out the world’s first warm blood perfusion liver transplantation with its innovative TransMedics Organ Care System Liver technology. Additionally, the perfusion systems market has a strong product pipeline with many products in clinical trials by leading market players in the U.S. and Europe. For instance, OrganOx Ltd. is developing METRA, which is under clinical study in the U.S., for automatic liver transportation and normothermic liver perfusion. The expected product approvals in the near future are anticipated to serve the healthcare industry with attractive growth opportunities.
Key players operating in the global perfusion systems market include Getinge AB, LivaNova plc, Medtronic plc, Terumo Corporation, Lifeline Scientific, Inc., XENIOS AG, XVIVO Perfusion AB, Spectrum Laboratories, Inc., Repligen Corporation, Merck KGaA, ALA Scientific Instruments, Inc. and Harvard Bioscience, Inc.
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