Pituitary - the master gland of human body is responsible for controlling crucial hormonal secretion, which, in turn, regulates other key aspects of the body such as temperature, growth, thyroid functioning, urination, and production of other hormones. It is a pea sized gland situated at the base of brain and is a major component of human body as it expedites the response towards the surrounding environment and settings.
Any deformity or damage to the pituitary gland can adversely impact the production and activity level of the above mentioned hormones, thereby affecting the body work process and stunting the outcomes especially in the case of growth hormone. Marred pituitary function leads to either over or under secretion of the somatropin that is the growth hormone. Its over secretion causes disfiguration in the body parts like hands, face, feet, etc. whereas, its deficiency impedes the growth of body parts/whole body, thus leading to disease states like dwarfism or gigantism.
It is observed that the growth hormone related problems usually affect children and teenagers, but it is seen to grip adults as well though to a lesser extent. The major factors which vitiate the pituitary operations thus impairing the GH role include kidney malfunction, tumors/cancer especially associated with brain. There are some other unknown causes as well which are termed as idiopathic. Earlier, to deal with these predicaments, growth hormone used to be extracted from the human cadavers but, as time passed and evolution of technology/tools/techniques/R&D took place, the extraction of GH also got altered and many novel innovations and discoveries were made in the respective field.
Nowadays, many leading companies are heavily involved in the R&D process for devising longer acting and sustained release versions of the somatropin which are produced using the recombinant technology. The competition prevalent in the respective industry is heating up day by day. The human growth hormone market is monopolized by a few players viz. Pfizer, NovoNordisk, Eli Lilly, Sandoz and Roche.
The global HGH report discusses the key ongoing trends like global agreement for Long-Acting Human Growth Hormone (HGH-CTP), increasing use of biosimilar version of drugs and continuous growth of recombinant growth hormones market. On the industry development front, the current inclination is towards developing better treatments for Alzheimer’s disease and advancements in needle free injections technology. Furthermore, the major factors driving the HGH market include rising cancer and CKD/ESRD cases and increasing healthcare expenditure on worldwide basis. In addition, a few factors posing challenges in front of the HGH industry are the problems in diagnosis of growth hormone deficiency, risks associated with use of recombinant growth hormone therapies and off-label HGH use which, to an extent, are hindering the growth and development of the same.
By combining SPSS Inc.’s data integration and analysis capabilities with our relevant findings, we have predicted the future growth of the industry. We employed various significant variables that have an impact on this industry and created regression models with SPSS Base to determine the future direction of the industry. Before deploying the regression model, the relationship between several independent or predictor variables and the dependent variable was analyzed using standard SPSS output, including charts, tables and tests.
Table of Contents
1. Human Growth Hormone
1.1 Physiological Effects of Growth Hormone
1.2 GH Secretion Control
1.3 GH Deficiency (GHD)
1.4 Therapeutic and Other Uses of GH/HGH
1.5 Recombinant Human Growth Hormone (rHGH)
2. Human Growth Hormone (HGH) Market Analysis
2.1 Global Market
Pediatric GHD Market
2.2 Regional Markets
2.3 VRS-317 Market Opportunity
2.4 TransCon-HGH Global Market Opportunity
3. Market Dynamics
3.1 Key Trends
3.1.1 Global Agreement for Long-Acting HGH-CTP
3.1.2 Increasing Use of Biosimilar Version of Drugs
3.1.3 Continuous Growth in rGH Market
3.2 Industry Developments
3.2.1 Developing Better Treatments for Alzheimer’s disease
3.2.2 Advancement in Needle Free Injection Technology
3.3 Growth Drivers
3.3.1 Increasing Cases of Chronic Kidney Disease (CKD)
3.3.2 Increasing Prevalence of Cancer
3.3.3 Rising Healthcare Expenditure
3.3.4 Increasing Global GDP
3.4.1 Problems in Diagnosis of GHD
3.4.2 Risks Associated With Recombinant Human GH Therapy
3.4.3 Off-Label Uses of rHGH Therapy not Well Defined
4. Competitive Landscape
5. Company Profiles
5.1 Roche Holdings AG
5.1.1 Business Overview
5.1.2 Financial Overview
5.1.3 Business Strategies
5.2 Novo Nordisk
5.2.1 Business Overview
5.2.2 Financial Overview
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