The process by which organs are kept viable outside of the organism from which they were removed (i.e., kept from decay by means of a chemical agent, cooling, or a fluid substitute that mimics the natural state within the organism). Global organ preservatives market is expected to witness a significant growth owing to increasing number of patients waiting for an organ transplant and rising incidences of vital organ failure (kidney, lungs, heart and etc.). The rising number of opportunities through strategic partnership with research organizations and medical institutions is projected to help the prominent players in expanding their consumer base.
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Major driving factors are rising multi-organ failure cases in the aging population, rising solid organ transplantation procedures and increasing government initiatives to promote organ donation. In addition, the growing focus on advancements in the medical sector is likely to contribute widely towards the development of the overall market in the next few years. Also, increasing age population will fuel the growth of organ preservation solutions market, due to the reason that the risk of organ failure in elderly people increases which supplements the demand for organ transplants. However, the limited medical reimbursements for organ transplantation and donation and the high cost of transplants are estimated to curb the growth of the overall market in the next few years.
On the basis of technique, the global organ preservatives market is categorized into; static cold storage (SCS), hypothermic perfusion preservation (HPP) and others. In this segment, static cold storage dominated the market by accounting for the largest share in 2016, owing to better long-term graft survival rates. However, hypothermic perfusion preservation technique is expected to witness the fastest growth in coming five years. It involves the machine profusion which provides a better short-term outcome, with lower rates of delayed graft function after transplantation of kidneys from all types of deceased donors. Therefore, interest in machine perfusion is increasing. In addition, it allows the continuous supply of solution to the preserved organ.
On the basis of preservation solution, the organ peservatives market segment is categorized into viaspan, custdiol HTK – (histidine-tryptophan-ketoglutarate) solution, renograf, perfadex, human biosystem (HBS) solution, lifor and others.
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Custdiol HTK is preferred in organ preservative solutions due to its properties such as; rapid homogenous cooling due to low viscosity and easier surgical handling due to excellent visibility. In addition, other properties include; the strong buffer (histidine), osmotic barrier (mannitol) and low-permeable amino acids (tryptophan and alpha-ketoglutaric acid) which help to stabilize cell membranes and may be substrates for anaerobic metabolism. Furthermore, the low viscosity of HTK solution provides more effective flushing and rapid cooling of organs.
On the basis of the organ type global organ preservation market is segmented into kidney lung, liver, heart and other organs. In this segment, kidney preservation attributed for the largest share owing to the increasing prevalence of kidney failures. As per American kidney fund, in 2015, Kidney disease is the 9TH leading cause of death in the United States. An estimated 31 million people in the United States (10% of the adult population) have chronic kidney disease (CKD).
North America accounted for largest share of this market in 2016 and is expected to witness the fastest growth in global organ peservatives market in coming five years. Growth in this region for this market is attributed to increasing awareness about organ donation resulting in an increase in organ donors. In addition, research and development in organ preservation solutions are also expected to fuel the growth in this market in this region.
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Europe is expected to be followed by North America and is expected to gain the second largest share in this market within the forecast period. The increasing awareness regarding the need for organ donation among the people and the rising number of initiatives taken by the government to encourage organ donation are expected to supplement the market growth in this region within the forecast period. In addition, the significant contribution from Spain is also expected to foster the growth of the market in the coming five years.
Asia-Pacific is expected to witness the fastest growth in this market in next five years. Growth in this region is expected to accelerate by increasing healthcare spending and increasing the aging population. Latin America and the Middle East & South Africa is also expected to show a positive growth in coming five years. In Latin America, a significant contribution from Brazil due to the increasing number of deceased and living organ donor is also expected to foster the growth of the market in the coming five years.
Some of the key players of green building market such as BioLife Solutions, Inc., BioTime, Inc., Claris Lifesciences Limited, CryoLife, Inc., Bristol-Myers Squibb, Lifeline Scientific, Dr. Franz Köhler Chemie GmbH, Teva Pharmaceutical Industries Ltd., Preservation Solutions, Inc., ToleroTech, Inc., among others.
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