Protein detection and quantification is a process which involves extraction, purification, labelling, and analysis of protein components. Protein detection and quantification is important before processing protein samples for separation and analysis of proteins by electrophoretic, chromatographic, and immunochemical techniques. The process of protein detection and quantification differs with respect to the amount and purity of protein and the accuracy required to detect and quantify it. Protein-copper chelation and secondary detection of the reduced copper and protein-dye binding, and direct detection of the color change associated with the bound dye are some examples of protein detection and quantification techniques.
The process of protein detection and quantification was first discovered in the 1950s with eminent physicists and chemists venturing into the field of biology to apply their techniques of detecting and analyzing the performances of proteins. The Bradford protein detection and quantification technique was the stepping stone toward developing more native solutions in analyzing proteins. The technique found out that the usage of detergents can keep the proteins in a state of solubility.
Increase in government funding to set up R&D centres for detecting and quantifying the performance of proteins is expected to play a critical role in driving the global protein detection and quantification market during the forecast period. Furthermore, rise in complex diseases has led to an increase in the need to study chronic diseases at the molecular level in order to detect their root cause, and also to find a solution to eliminate these diseases by producing suitable antigens.
The possibilities of flaws in the methods to detect and quantify proteins is a key drawback which is likely to restrain the global protein detection and quantification market during the forecast period. Moreover, the process of purification and analysis of proteins during the detection and quantification process might lead to low level crossover contamination of the proteins.
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The global protein detection and quantification market has been segmented on the basis of type of technology, type of product, application, end-use industry, and region.
In terms of type of technology, the global protein detection and quantification market can be segmented into colorimetric assays, chromatography, immunological methods, spectroscopy instruments, mass spectrometry, and others.
In terms of type of product, the global protein detection and quantification market can be segmented into instruments, kits, consumables, and services.
In terms of application, the global protein detection and quantification market can be segmented into drug discovery and development, clinical diagnosis, and others. The drug discovery and development segment is expected to acquire considerable market share owing to increase in the number of complex diseases and research and development activities to detect the occurrences of these diseases.
In terms of end-use industry, the global protein detection and quantification market can be segmented into academic research institutes, contract research organization, biotechnology and pharmaceutical companies, and others.
In terms of region, the global protein detection and quantification market can be segmented into North America, Europe, Asia Pacific, Middle East &Africa, and Latin America. North America is estimated to dominate the global protein detection and quantification market followed by Europe due to the presence of a significant number of R&D projects undertaken in the region. In North America, the U.S is anticipated to lead the market, whereas in Europe, Germany, followed by the U.K are projected to lead the protein detection and quantification market.
The global protein detection and quantification market is highly consolidated with the presence of few leading players who dominate the market. Patent issues restrict the entry of new players and thereby restrict the market. Key players operating in the global protein detection and quantification market are Bio-Rad Laboratories, Inc., GE Healthcare, PerkinElmer Inc., Inanovate, Thermo Fisher Scientific, Danaher, Merck & Co., Inc., Shimadzu Corporation, and RayBiotech, Inc.
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