Optimizing Treatment for Bone Metastases in Patients with Advanced Cancers Analysis

Understand current practice patterns related to bone metastases in  patients with advanced cancers. Patient specific unfolding case  scenarios presented to 174 high-prescribing oncologists on the treatment  of bones metastases in patients with advanced stages of cancer  including breast, renal cell carcinoma, and prostate. 

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The survey was presented for their responses on clinical decisions. Oncologists were asked to respond to open-ended questions concerning their choices of treatment regimens, factors that influence their decisions, and barriers to optimal patient management. The survey was administered electronically by Qualtrics survey software between December 15, 2010 and March 31, 2011. Patient progression reveals decisions in treatment throughout patient stages.

Table of Contents

Executive SummaryIntroduction
Respondent DemographicsEligibility Criteria for Survey ParticipationGender of Survey RespondentsYears since Medical School GraduationPractice SettingsPractices in NCI Cancer CentersGeographic SettingsNumber of Physicians in Practice GroupsMinimal Acceptable Level of Evidence in Determining Treatment Regimen Treatment of Bone Metasteses in Patients with Advanced Breast CancersPatient with ER/PR positive HER2/neu negative metastatic breast cancerOther than analgesics, treatment of hip pain in a patient with ER/PR positive HER2/neu negative metastatic breast cancer

Treatment of Bone Metastases in Patients with Advanced Breast CancersPatient with metastatic breast cancer with multiple comorbiditiesTreatment in addition to the aromatase inhibitor for patient’s metastatic breast cancer with multiple comorbidities
Treatment of Bone Metastases in Advanced Renal Cell CancerTreatment of good to moderate prognosis renal cell cancerInitial treatment regimen chosen following surgeryTreatment of Bone Metastases in Advanced Prostate CancerTreatment of a patient with increased PSA and adenocarcinomaTests to be performed

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