US Oncologist Survey: Optimizing Treatment for Large Cell Lymphoma - Analysis

Two patient specific case scenarios on advanced non-Hodgkin’s lymphoma involving patients with a) relapsed large cell lymphoma and b) large cell lymphoma with compromised cardiac function that progresses throughout the report, presented to 158 high-prescribing oncologists for their open responses on clinical decisions.

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Treatment decisions for advanced stages of cancer are difficult to track as information quickly changes along with the introduction of new products that all have an impact oncologists’ choices. This report is part of a series of oncology reports that allow you to see what is actually happening at the patient level for different types of patients presenting with a wide range of issues in advanced stages of cancer. 

Table of Contents

Executive Summary

Chapter 1: IntroductionTable 1. Treatment Options in Non-Hodgkin’s Lymphoma

Chapter 2: Respondent DemographicsTable 2. Eligibility Criteria for Survey ParticipationFigure 2.1 Gender of Survey RespondentsFigure 2.2 Years since Medical School GraduationFigure 2.3 Practice SettingsFigure 2.4 Practices in NCI Cancer CentersFigure 2.5 Geographic SettingsFigure 2.7 Number of Physicians in Practice GroupsFigure 2.6 Survey Respondents by State’s Non-Hodgkin’s Lymphoma MortalityFigure 2.7 Number of Physicians in Practice GroupsFigure 2.8 Minimal Acceptable Level of Evidence in Determining Treatment Regimen

Chapter 3: Patient with Relapsed Large Cell LymphomaFigure 3.1 Barriers to optimal care of large cell lymphomaFigure 3.2 Confidence in treatmentFigure 3.3 First line treatment approach to patient with large cell lymphomaFigure 3.4 Factors that influence treatment decisionFigure 3.5 Preferred R-CHOP regimenFigure 3.6 Next step in management following R-CHOPFigure 3.7 Treatment for progressing B-cell large cell lymphomaFigure 3.8 Factors influencing treatment decisionFigure 3.9 Treatment following response then relapse from second-line therapy

Chapter 4: Patient with Large Cell Lymphoma with Compromised Cardiac FunctionFigure 4.1 Confidence in treatment for large cell lymphoma with compromised cardiac functionFigure 4.2 Treatment approach for large cell lymphoma with compromised cardiac functionFigure 4.3 Factors influencing treatment of large cell lymphoma with compromised cardiac functionFigure 4.4 Treatment approach for large cell lymphoma with compromised cardiac functionFigure 4.5 Second-line treatment for large cell lymphoma with compromised cardiac function

Chapter 5: SummaryAppendix A: Survey Instrument

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