Press release -
Hernia Publishes a Unique Three Year Pre-Clinical Study of absorbable TIGR® Matrix Surgical Mesh Versus a Permanent Mesh
The study, which was presented Online First in Hernia - The World Journal of Hernia and Abdominal Wall Surgery, describes the results of three years of functional implantation of TIGR® Matrix versus a permanent mesh in a sheep model.
This is the longest preclinical evidence ever published on surgical mesh, and it reveals key differences in outcome when comparing TIGR® Matrix to a permanent mesh. As TIGR® Matrix was absorbed over time, it was replaced by connective tissue that had higher collagen content than that surrounding the permanent control mesh. Over time, the foreign-body response to TIGR® Matrix declined significantly while it remained persistent in the control group.
“As TIGR® Matrix is the worlds first long-term absorbable mesh and also the first surgical mesh product with time-dependent mechanical characteristics, we wanted to substantiate how the unique design affects the tissue in terms of regenerated structure and stability.” – said Henrik Hjort, first author and co-inventor of TIGR® Matrix. “We believe that the dual-fibre mechanics and resultant gradually increasing compliance can lead to long-lasting results which are indicated by the lack of defect recurrences in this study. A range of clinical studies are underway to examine the results of repair using TIGR® Matrix in a variety of soft tissue reinforcement applications to further demonstrate the benefits to the surgical community.”
As stated in the publication: “As the resorbable test mesh gradually degraded it was replaced by a newly formed collagen matrix with an increasing ratio of collagen type I/III, indicating a continuous remodeling of the collagen towards a strong connective tissue.” Furthermore: “The general connective tissue layer formed was thicker around the test mesh compared to the control.” Hjort H, et al. (2011) Hernia. doi: 10.1007/s10029-011-0885-y.
The study was performed at Biomatech, an independent contract research company that is part of the NAMSA group.
Hernia – The World Journal of Hernia and Abdominal Wall Surgery is published by Springer (www.springerlink.com) and the article link can be found here: http://www.springerlink.com/content/c033k26015677312/
TIGR® Matrix Surgical Mesh is available for sale in the U.S and Europe.
Topics
- Health, Health Care, Pharmaceuticals
Categories
- absorbable
- hernia
- matrix
- mesh
- novus scientific
- resorbable
- surgical mesh
- synthetic
- tigr matrix
About Novus Scientific
Novus Scientific (www.novusscientific.com) is an innovator in the development and commercialization of resorbable (100% absorbable) synthetic medical devices. Global HQ is in Singapore while European Headquarters and the core R&D function are in Uppsala, Sweden. The company’s roots are Swedish as all the founders of Novus Scientific are previous owners / senior managers / members of the soft tissue-engineering project within Uppsala-based, Radi Medical Systems AB (now owned by St. Jude Medical Inc). The US Division, Novus Scientific, Inc. is headquartered near Boston, one of the world’s foremost medical research cities. From this hub, Novus Scientific, Inc. will distribute TIGR® Matrix Surgical Mesh throughout the United States.
TIGR® Matrix - The world’s 1st long-term resorbable, 100% absorbable synthetic mesh with unique patented dual-fiber construction, designed for gradually increasing mechanical compliance.
TIGR® is a registered trademark of Novus Scientific Pte. Ltd
