Launch of a unique multichannel head allowing full process control.

To speed up monitored processes where highly parallel liquid handling is required, Hamilton has developed the CO-RE 96 probe head 1000μl TADM with a volume range from 1 to 1000 microliters.
Four channels are equipped with sensors for capacitive liquid level detection (cLLD). As either the first two or the last two columns of a 96 well plate are often used for standards and controls, the four cLLD channels are on positions A1 B2 and H12 G11 (with respect to a 96 MTP). In addition, each of the 96 Channels equipped with a pressure sensor enabling the use of HAMILTON’s patented TADM feature.

Due to the ability of real time monitoring during Pipetting, it is now possible to increase the process stability.During routine pipetting, errors are reported in real-time when the measured pressure exceeds high and low pressure limit bands. The system can then simply record the errors or react to them.TADM enables Real Time Monitoring of the Aspiration and Dispensing Process Pressure Controlled

Aspiration detects at any time:

- Blood Clots
- Short Sample
- No Sample
- Leakage in the System

Pressure Controlled Dispensing detects at any time:

- Blocked Tip
- Short Sample
- Lost Sample
- Leakage in the System

Applications

Important applications of the CO-RE 96 probe head 1000μl TADM include monitored plate copying processes, pipetting of standards and controls into single columns of 96 well plates and plate reformatting (for example of 96 well to 384 well plates). Because of the real time monitoring the CO-RE 96 probe head 1000μl TADM can provide significant time savings in processes such as serial dilution over a 96 well plate and set-up of PCR or sequencing reactions in 96 well plates.