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The Importance of Large Scale Biobanking in Region Skane

Press Release   •   Feb 26, 2013 08:50 CET

With the automated liquid handling and pipetting platforms from Hamilton Robotics, FoU Centre at Skåne university hospital in Lund has develop and implemented a high density
384-format sample tube system for the preservation and archiving of clinical
blood samples. This system will be used within the major hospitals in Region
Skåne for Centralized BioBanking (Reference 1-2).

FoU Centre
Skåne have developed a fully automated Blood fractionation Processing Work Flow- aliquoting 70-µL volumes fractions of; EDTA, Li-heparin, and citrate plasma, as well as serum, buffy coat and erythrocyte fractions. Samples from patients are processed and aliquoted in 384-sample racks automatically. The FoU Centre Skåne development team has demonstrated that the validated system is working well and superior to manual handling, thus making it suitable handling samples for Biobanking. The “BIG3” Study,Cardiovascular Diaseas, Lung Cancer and Chronic Obstructive Pulmonary Disease (COPD); will be the first user of the infrastructure. Big3 is a prospective cohort study that will do high density data sampling and biobanking from 10 000 participants. Within this study, blood samples were analyzed quantifying 23 common markers used in everyday healthcare around the world.

By utilizing this new biobanking work-flow, we have so far processed more than 100.000 sample types with the 384 high density formats, and this will be the future standard in modern clinical chemistry biobanking. The standardization of sample preparation and storage will provide measures of quality needed to ensure that the sample sets in the future will be an analysis resource globally for the community, the science and for the development of new medicines and diagnostics,  in addition to novel methodologies and the development of innovative technology platforms.

  1. Malm
         J., , Végvári A, Rezei M., Upton P., Danmyr P., Nilsson R., Steinfelder
         E.,  Marko-Varga G., J.
         Proteomics.,  76, 116-124, 2012 “Large Scale Biobanking of Blood – The
         importance of high density sample processing procedures”

  2. Marko-Varga
         G, Végvári A, Welinder C, Rezei M., Edula G., Svensson K., Belting M.,
         Laurell T., Fehniger T. E., J. Proteome Res., 2012, 11, 5124-34, “Clinical
         Protein Science: Utilization of Biobank Resources and Examples of Current


HAMILTON Robotics designs and manufactures fully automated robotic systems. The products range from unique, custom laboratory automation solutions (turnkey solutions) on standard applications validated through partnership programs with renowned biotechnology companies as well as OEM solutions to the top ten diagnostic companies. The combination of great know-how of the engineers and experienced scientists in biotechnology, drug discovery, diagnostics and software as well as the constant development and improvement allows HAMILTON to satisfy customers’ needs. Precision, innovation, reliability and quality are the philosophy of the technology leader HAMILTON Robotics.