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Chronic Myelocytic Leukemia (CML, Chronic Myeloid Leukemia) - Pipeline Review, H2 2015 Now Available at iData Insights
Chronic Myelocytic Leukemia (CML, Chronic Myeloid Leukemia) - Pipeline Review, H2 2015 Summary Global Markets Direct s, Chronic Myelocytic Leukemia (CML, Chronic Myeloid Leukemia) - Pipeline Review, H2 2015 , provides an overview of the Chronic Myelocytic Leukemia (CML, Chronic Myeloid Leukemia) s therapeutic pipeline. This report provides comprehensive information on the therapeutic development for Chronic Myelocytic Leukemia (CML, Chronic Myeloid Leukemia), complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Chronic Myelocytic Leukemia (CML, Chronic Myeloid Leukemia) and special features on late-stage and discontinued projects. Global Markets Directs report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Directs proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct s team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease. Scope - The report provides a snapshot of the global therapeutic landscape of Chronic Myelocytic Leukemia (CML, Chronic Myeloid Leukemia) - The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved in the therapeutics development for Chronic Myelocytic Leukemia (CML, Chronic Myeloid Leukemia) and enlists all their major and minor projects - The report summarizes all the dormant and discontinued pipeline projects - A review of the Chronic Myelocytic Leukemia (CML, Chronic Myeloid Leukemia) products under development by companies and universities/research institutes based on information derived from company and industry-specific sources - Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages - A detailed assessment of monotherapy and combination therapy pipeline projects - Coverage of the Chronic Myelocytic Leukemia (CML, Chronic Myeloid Leukemia) pipeline on the basis of target, MoA, route of administration and molecule type - Latest news and deals relating related to pipeline products Reasons to buy - Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Develop strategic initiatives by understanding the focus areas of leading companies - Identify and understand important and diverse types of therapeutics under development for Chronic Myelocytic Leukemia (CML, Chronic Myeloid Leukemia) - Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline - Devise corrective measures for pipeline projects by understanding Chronic Myelocytic Leukemia (CML, Chronic Myeloid Leukemia) pipeline depth and focus of Indication therapeutics - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline.
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Table of Contents
Introduction 10
Global Markets Direct Report Coverage 10
Chronic Myelocytic Leukemia (CML, Chronic Myeloid Leukemia) Overview 11
Therapeutics Development 12
Pipeline Products for Chronic Myelocytic Leukemia (CML, Chronic Myeloid Leukemia) - Overview 12
Pipeline Products for Chronic Myelocytic Leukemia (CML, Chronic Myeloid Leukemia) - Comparative Analysis 13
Chronic Myelocytic Leukemia (CML, Chronic Myeloid Leukemia) - Therapeutics under Development by Companies 14
Chronic Myelocytic Leukemia (CML, Chronic Myeloid Leukemia) - Therapeutics under Investigation by Universities/Institutes 19
Chronic Myelocytic Leukemia (CML, Chronic Myeloid Leukemia) - Pipeline Products Glance 21
Late Stage Products 21
Clinical Stage Products 22
Early Stage Products 23
Unknown Stage Products 24
Chronic Myelocytic Leukemia (CML, Chronic Myeloid Leukemia) - Products under Development by Companies 25
Chronic Myelocytic Leukemia (CML, Chronic Myeloid Leukemia) - Products under Investigation by Universities/Institutes 30
Chronic Myelocytic Leukemia (CML, Chronic Myeloid Leukemia) - Companies Involved in Therapeutics Development 32
Altor BioScience Corporation 32
Aprea AB 33
arGEN-X BV 34
Ariad Pharmaceuticals, Inc. 35
Array BioPharma Inc. 36
Astex Pharmaceuticals, Inc. 37
Baxalta Incorporated 38
Bellicum Pharmaceuticals, Inc. 39
Bio-Path Holdings, Inc. 40
Biogenomics Limited 41
BioLineRx, Ltd. 42
BioSight Ltd. 43
Boston Biomedical, Inc. 44
Bristol-Myers Squibb Company 45
Cantargia AB 46
Celgene Corporation 47
Constellation Pharmaceuticals, Inc. 48
Daiichi Sankyo Company, Limited 49
Deciphera Pharmaceuticals, LLC 50
Eisai Co., Ltd. 51
EpiZyme, Inc. 52
Galena Biopharma, Inc. 53
Gamida Cell Ltd. 54
HEC Pharm Co., Ltd. 55
Hybrigenics S.A. 56
Ilyang Pharmaceutical Co., Ltd 57
Incyte Corporation 58
Jiangsu Hansoh Pharmaceutical Co., Ltd. 59
Juno Therapeutics Inc. 60
JW Pharmaceutical Corporation 61
KaloBios Pharmaceuticals, Inc. 62
Karyopharm Therapeutics, Inc. 63
Lixte Biotechnology Holdings, Inc. 64
Millennium Pharmaceuticals, Inc. 65
Mirna Therapeutics, Inc. 66
Natco Pharma Limited 67
Novartis AG 68
Onconova Therapeutics, Inc. 69
Ono Pharmaceutical Co., Ltd. 70
Oribase Pharma 71
Pfizer Inc. 72
Pharma Mar, S.A. 73
PharmaEssentia Corporation 74
Selvita SA 75
Shenogen Pharma Group Ltd. 76
Stemline Therapeutics, Inc. 77
Sun Pharma Advanced Research Company Ltd. 78
Targazyme, Inc. 79
Teva Pharmaceutical Industries Limited 80
Threshold Pharmaceuticals, Inc. 81
Chronic Myelocytic Leukemia (CML, Chronic Myeloid Leukemia) - Therapeutics Assessment 82
Assessment by Monotherapy Products 82
Assessment by Combination Products 83
Assessment by Target 84
Assessment by Mechanism of Action 89
Assessment by Route of Administration 93
Assessment by Molecule Type 95
Drug Profiles 97
(camptothecin + podofilox) - Drug Profile 97
ABL-001 - Drug Profile 98
AIC-47 - Drug Profile 99
ALT-803 - Drug Profile 100
anagrelide hydrochloride CR - Drug Profile 103
APR-246 - Drug Profile 104
ARGX-110 - Drug Profile 106
azacitidine - Drug Profile 109
binimetinib - Drug Profile 113
BL-8040 - Drug Profile 118
BMS-833923 - Drug Profile 120
bosutinib - Drug Profile 122
BP-100101 - Drug Profile 125
BPX-501 - Drug Profile 127
BST-236 - Drug Profile 129
CAN-04 - Drug Profile 130
Cell Therapy to Target GM-CSF for Oncology - Drug Profile 132
Cell Therapy to Target Tumor Associated Antigen for Hematopoietic Malignancies - Drug Profile 134
CPI-0610 - Drug Profile 135
CT-413 - Drug Profile 136
CWP-291 - Drug Profile 137
D-12PGJ3 - Drug Profile 139
D-824 - Drug Profile 140
danusertib - Drug Profile 141
Dendritic Cell Therapy for Chronic Myeloid Leukemia - Drug Profile 143
Dendritic Cell Therapy for Hematological Malignancies - Drug Profile 144
Dendritic Cell Therapy for Oncology - Drug Profile 145
Dendritic Cell Therapy for Oncology and Infectious Disease - Drug Profile 146
Dendritic Cell Therapy to Target WT1 for Oncology - Drug Profile 147
DS-3032 - Drug Profile 148
E-6201 - Drug Profile 149
erismodegib - Drug Profile 151
ETC-027 - Drug Profile 154
ETC-219 - Drug Profile 155
evofosfamide - Drug Profile 156
flumatinib mesylate - Drug Profile 164
Gene Therapy for Oncology - Drug Profile 165
guadecitabine - Drug Profile 166
Hu8F4 - Drug Profile 170
inecalcitol - Drug Profile 171
inotuzumab ozogamicin - Drug Profile 174
interferon alfa-2a - Drug Profile 176
interferon alfa-2b - Drug Profile 177
ipilimumab - Drug Profile 178
ixazomib citrate - Drug Profile 183
JTCR-016 - Drug Profile 187
KB-004 - Drug Profile 188
LB-100 - Drug Profile 190
LB-102 - Drug Profile 192
lirilumab - Drug Profile 194
lurbinectedin - Drug Profile 196
MJ-05 - Drug Profile 199
MRX-102 - Drug Profile 200
MRX-34 - Drug Profile 202
napabucasin - Drug Profile 204
NiCord - Drug Profile 207
nivolumab - Drug Profile 208
NOV-120501 - Drug Profile 216
NRCAN-019 - Drug Profile 217
omacetaxine mepesuccinate - Drug Profile 219
ORB-0001 - Drug Profile 222
pegaspargase - Drug Profile 223
PF-114 - Drug Profile 225
pinometostat - Drug Profile 226
ponatinib hydrochloride - Drug Profile 229
PRI-724 - Drug Profile 232
radotinib - Drug Profile 234
rebastinib tosylate - Drug Profile 236
rigosertib sodium - Drug Profile 238
ropeginterferon alfa-2b - Drug Profile 243
ruxolitinib phosphate - Drug Profile 246
SEL-24B489 - Drug Profile 251
selinexor - Drug Profile 252
SL-401 - Drug Profile 258
SL-501 - Drug Profile 260
Small Molecule to Inhibit ADAR1 for Chronic Myeloid Leukemia - Drug Profile 261
Small Molecules to Inhibit Abl Tyrosine Kinase for CML - Drug Profile 262
Small Molecules to Inhibit BCR-ABL for CML - Drug Profile 263
Small Molecules to Inhibit Bcr-Abl for CML and Pancreatic Cancer - Drug Profile 264
Small Molecules to Inhibit BRCA2/Rad51 Interaction for Cancer - Drug Profile 265
SNG-1153 - Drug Profile 266
SNG-162 - Drug Profile 267
SUNK-706 - Drug Profile 269
TR-120 - Drug Profile 270
trametinib dimethyl sulfoxide - Drug Profile 271
TZ-101 - Drug Profile 274
Vaccine to Target Bcr-Abl Tyrosine Kinase for Chronic Myeloid Leukemia - Drug Profile 276
Vaccine to Target Wilms Tumor Protein for Oncology - Drug Profile 277
Vaccine to Target WT1 for CML and AML - Drug Profile 278
Vaccine to Target WT1 for Oncology - Drug Profile 279
Chronic Myelocytic Leukemia (CML, Chronic Myeloid Leukemia) - Recent Pipeline Updates 280
Chronic Myelocytic Leukemia (CML, Chronic Myeloid Leukemia) - Dormant Projects 414
Chronic Myelocytic Leukemia (CML, Chronic Myeloid Leukemia) - Discontinued Products 420
Chronic Myelocytic Leukemia (CML, Chronic Myeloid Leukemia) - Product Development Milestones 422
Featured News & Press Releases 422
Appendix 433
Methodology 433
Coverage 433
Secondary Research 433
Primary Research 433
Expert Panel Validation 433
Contact Us 433
Disclaimer 434"
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