New application note available - Whole Genome and Transcriptome Analysis for Leukemia Diagnostics

The rationale behind the automation of the assay is mainly in terms of a quality improvement and enhancement of productivity, provided by minimizing the bias that might be otherwise introduced by manual library preparation. Moreover, the automated system is sufficiently flexible to adapt and therefore easily meet evolving needs.

• High throughput workflow for 5000 patients
• Standardization of whole genome and transcriptome workflows for sequencing
• Lower bias compared with manual sample preparation

Library preparation is a key requirement for many Next Generation Sequencing (NGS) applications such as the sequenc­ing and analysis of clinical samples; an essential part of medi­cal diagnostics.

The automation of the NGS workflow, including on-deck in­cubations and plate shaking, plate stacking, and large tip in­ventory, significantly reduces hands-on time and allows for the processing of up to 96 samples in a single run. Proper placement of reagents, plates and tips are guaranteed by au­tomated barcode verification. The user can also define in-line controls, upload a worklist with the combination of index and samples, select the desired fragmentation time, and define the appropriate index adapters. The automated error handling and the easy-to-use graphical interface ensure a smooth setup of the experimental run, which can also be started and stopped at specific steps within the process.

Please contact us at info.nordic@hamilton.ch for more information and to receive an offer. Please also look at the attached PDF for more information.