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ATROSAB, a humanized antagonistic anti-tumor necrosis factor receptor one specific antibody
University of Stuttgart, Institute of Cell Biology and Immunology: A humanized IgG1 version (ATROSAB) of a murine TNFR1-selective antagonistic antibody (H398) has been generated. The ATROSAB shows identical binding characteristics and sub-nanomolar affinity to both human and rhesus TNFR1.
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Topics
- Medical research
Categories
- antibodies
- biosensors
- receptors
