Document -
Large Scale Production of Botulium Neurotoxin Type A Binding Domain and Characterization by Quartz Crystal Microbalance Biosensor Technology
University of California, San Fransisco (UCSF): A method has been optimized to extract Botulinum toxin A from the inclusion body, refold it into active form and purify it using ion exchange chromatography. A rapid immunoassay was also developed to facilitate monitoring of active Botulinum toxin A during purification, using Attana's quartz crystal microbalance sensor technology.
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License:
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- File format: .pdf
Topics
- Medical research
Categories
- antibodies
- drug development
- quartz crystal microbalance
