Atrial fibrillation increases the risk of stroke. Treatment with oral anticoagulation reduces this risk but instead increases the risk of bleeding. Today, a new blood test based tool enabling better and more individualized stroke prevention treatment is presented at a congress in Chicago, and simultaneously published in the top-ranked medical journal The Lancet.
Cancer therapy is often hampered by the accumulation of fluids in and around the tumour, which is caused by leakage from the blood vessels in the tumour. Researchers at Uppsala University now show how leakage from blood vessels is regulated. They have identified a novel mechanism whereby leakage can be suppressed to improve the result of chemotherapy and reduce the spread of tumours in mice.
One may expect a creature that darts around its habitat to be capable of perceiving rapid changes as well. Yet birds are famed more for their good visual acuity. Joint research by Uppsala University, Stockholm University and SLU now shows that, in small passerines (perching birds) in the wild, vision is considerably faster than in any other vertebrates .
The saint's legend speaks of a king who died a dramatic death in battle outside the church where he had just celebrated mass. But what can modern science tell us about his remains? A joint research project headed by Uppsala University now reveals more of the health condition of the medieval king Erik, what he looked like, where he lived and what the circumstances of his death were.
A difference of one hundredth of a percent in fitness is sufficient to select between winners and losers in evolution. For the first time researchers have quantified the tiny selective forces that shape bacterial genomes. The story is published today in the prestigious journal PLoS Genetics.
Human communication is powered by rules for combining words to generate novel meanings. Such syntactical rules have long been assumed to be unique humans. A new study, published in Nature Communications, show that Japanese great tits combine their calls using specific rules to communicate important compound messages.
For the first time, researchers have succeeded in passing an antibody through the blood-brain barrier to act as a tracer for PET imaging of the brain. This resulted in more precise information being obtained than with regular radioactive tracers. The study provides hope for more effective diagnosis of early onset Alzheimer’s disease and improvements in monitoring the effects of medication.
Individuals subjected to chronic low-dose exposure to organochlorine pesticides show and increased risk to obtain a future diagnosis of cognitive impairment. This is shown in a international study now published in Environmental International.
Sometimes so-called synonymous mutations occur in DNA. These do not lead to a change in the protein sequence but which may still have major negative effects on the ability of bacteria to survive. New research from Uppsala University has now shown that an organism can efficiently compensate for the negative effects. These findings have been published in the journal Molecular Biology and Evolution.
They live several kilometers under the surface of the earth, need no light or oxygen and can only be seen in a microscope. By sequencing genomes of a newly discovered group of microbes, the Hadesarchaea, an international team of researchers have found out how these microorganisms make a living in the deep subsurface biosphere of our planet.
The human desire to master light has taken us from controlling fire to building global optical networks. But several questions still remain to be answered. At this year's Celsius-Linné lectures on February 18, top international researchers Professor Eli Yablonovitch and Professor Lene Vestergaard Hau will present pioneering ways to manage and manipulate light for use in countless areas.
A new species of bird has been described in north-eastern India and adjacent parts of China by a team of scientists from Sweden, China, the US, India and Russia, headed by Professor Per Alström, Uppsala University, and Swedish University of Agricultural Science, SLU. The bird has been named the Himalayan Forest Thrush, Zoothera salimalii.
