Researchers and doctors at Uppsala University, along with Swedish and international collaboration partners, have found gene variants that predict the risk of a serious adverse reaction to drugs used for the treatment of hyperthyroidism. The results are published in The Lancet Diabetes & Endocrinology.
How species genetically adapt to their environment is a central question related to the evolution of biodiversity. In a new study scientists at Uppsala University and their colleagues report that whole genome sequencing of Atlantic and Baltic herring revealed hundreds of loci underlying adaptation to the brackish Baltic Sea or timing of reproduction. The study is published today in eLife.
The most characteristic feature of Darwin’s finches is the diversification of beak morphology that has allowed these species to expand their utilization of food resources in the Galápagos archipelago. A team of scientists from Uppsala University and Princeton University has now identified a gene that explains variation in beak size within and among species. The study is published in Science.
In rare instances, DNA is known to have jumped from one species to another. If a parasite’s DNA jumps to its host’s genome, it could leave evidence of that interaction that could be found millions of years later — a DNA ‘fossil’ of sorts. Researchers from Uppsala University have discovered a new type of so-called transposable element that occurred in the genomes of certain birds and nematodes.
Using unique demographic records on 140,600 reproducing individuals from the Utah Population Database (USA), a research team led from Uppsala University has come to the conclusion that lowered birth rates are one reason why women outlive men in today’s societies. The study is published in Scientific Reports.
The Johan Skytte Prize annually recognizes the most valuable contribution to the field of Political Science. This year’s prize is awarded to Professor Jon Elster, Robert K. Merton Professor in Social Sciences at Columbia University and titular professor at College de France, Paris.
Atrial fibrillation increases the risk of stroke. Treatment with oral anticoagulation reduces this risk but instead increases the risk of bleeding. Today, a new blood test based tool enabling better and more individualized stroke prevention treatment is presented at a congress in Chicago, and simultaneously published in the top-ranked medical journal The Lancet.
Cancer therapy is often hampered by the accumulation of fluids in and around the tumour, which is caused by leakage from the blood vessels in the tumour. Researchers at Uppsala University now show how leakage from blood vessels is regulated. They have identified a novel mechanism whereby leakage can be suppressed to improve the result of chemotherapy and reduce the spread of tumours in mice.
One may expect a creature that darts around its habitat to be capable of perceiving rapid changes as well. Yet birds are famed more for their good visual acuity. Joint research by Uppsala University, Stockholm University and SLU now shows that, in small passerines (perching birds) in the wild, vision is considerably faster than in any other vertebrates .
The saint's legend speaks of a king who died a dramatic death in battle outside the church where he had just celebrated mass. But what can modern science tell us about his remains? A joint research project headed by Uppsala University now reveals more of the health condition of the medieval king Erik, what he looked like, where he lived and what the circumstances of his death were.
A difference of one hundredth of a percent in fitness is sufficient to select between winners and losers in evolution. For the first time researchers have quantified the tiny selective forces that shape bacterial genomes. The story is published today in the prestigious journal PLoS Genetics.
Human communication is powered by rules for combining words to generate novel meanings. Such syntactical rules have long been assumed to be unique humans. A new study, published in Nature Communications, show that Japanese great tits combine their calls using specific rules to communicate important compound messages.