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  • Genetic effects are influenced by lifestyle

    The risk for developing obesity is influenced by our lifestyle as well as our genes. In a new study from Uppsala University, researchers show that our genetic risk for obesity is not static, but is influenced by our lifestyle. Results from the study have been published in the scientific journal PLOS Genetics.

  • Fossil footprints challenge established theories of human evolution

    Newly discovered human-like footprints from Crete may put the established narrative of early human evolution to the test. The footprints are approximately 5.7 million years old and were made at a time when previous research puts our ancestors in Africa – with ape-like feet.

  • ​Millions of novel genetic variants found in 1000 Swedish individuals

    An extensive exercise to map genetic variation in Sweden has found 33 million genetic variants, 10 million of which are novel. Large-scale DNA sequencing methods were used to analyse the whole genome of 1000 individuals from different parts of the country. The study was led by researchers at Uppsala University, who have published their findings in the European Journal of Human Genetics.

  • New ultrafast method for determining antibiotic resistance

    Researchers at Uppsala University have developed a new method for very rapidly determining whether infection-causing bacteria are resistant or susceptible to antibiotics. The findings have now been published in the US journal Proceedings of the National Academy of Sciences (PNAS).

  • ​Functions at old age are influenced by previous lifestyle

    "Which factors increase the chance of aging with well-maintained functions?" Older men who never smoked, avoided obesity and had held a healthy Mediterranean-inspired diet have good chances of maintaining their independence at a very high age.

  • ​Blocking of an enzyme stops brain tumour cells from growing

    By blocking of an enzyme that affects the cellular microenvironment it is possible to stop brain tumour cells from growing. This is shown in a new study published in the journal Molecular Cancer Therapeutics by researchers at Uppsala University in collaboration with researchers in Haifa, Israel and Brisbane, Australia.

  • ​Shortcut method in drug development

    In the latest issue of the journal Proceedings of the National Academy of Sciences (PNAS), a research group at Uppsala University presents a new, small-scale method that may become a smart shortcut for determining the “bioavailability” of a pharmaceutical drug within cells.

  • Insulin release is controlled by the amount of Epac2A at the secretory vesicles

    Specialized beta cells in the pancreas release the hormone insulin to control our blood glucose levels, and failure of this mechanism is central to the development of type-2 diabetes. How much and when insulin is released depends on a complex system of messenger molecules and proteins that is not well understood.

  • Less myocardial infarctions during summer vacation - more on Mondays and winter holidays

    Time periods by calendar related to perceived stress are associated with the incidence rate of myocardial infarction (MI), says a new nationwide registry study of the Swedish population. Compared to control days, the daily incidence rate of MI was higher during the winter holidays, and on Mondays, whereas rates were lower during weekends and during the summer vacation in July.

  • Diabetes patients still produce insulin

    Some insulin is still produced in almost half of the patients that have had type 1 diabetes for more than ten years. The study conducted by researchers at Uppsala University in Sweden has now been published online by the medical journal Diabetes Care.

  • Genetic differences across species guide vocal learning in juvenile songbirds

    Juvenile birds discriminate and selectively learn their own species’ songs even when primarily exposed to the songs of other species, but the underlying mechanism has remained unknown. A new study, by researchers at Uppsala University, shows that song discrimination arises due to genetic differences between species, rather than early learning or other mechanisms.

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