Cellular lipids are more efficient than proteins in trapping most drugs and hence reducing the free intracellular drug concentration. This is shown by researchers at Uppsala University in an article published in Molecular Pharmaceutic.
One strategy for cancer therapy is to inhibit the development of blood vessels in the tumour. Researchers at Uppsala University show in a new study how the protein CD93 interacts with the protein network that is required for tumour vessels to form properly. Blocking this interaction could be used as a means to hamper blood vessel development and slow down the cancer.
A new study published in Nature Communications shows that infants who are later diagnosed with autism react more strongly to sudden changes in light. This finding provides support for the view that sensory processing plays an important role in the development of the disorder.
In a new study published by Nature, an international team of researchers led by Uppsala University in Sweden proposes a new evolutionary origin for mitochondria – also known as the ‘powerhouses of the cell’. Mitochondria are energy-converting organelles that have played key roles in the emergence of complex cellular life on Earth.
Antibiotic-resistant bacteria are a global and growing problem in health care. To be able to prevent further development of resistance developing, it is important to understand where and how antibiotic resistance in bacteria arises. New research from Uppsala University shows that low concentrations of antibiotics, too, can cause high antibiotic resistance to develop in bacteria.
A handful of tiny teeth have led scientists to identify the most distant ancestor of today’s kangaroos. The fossils were found in the desert heart of Australia, and then hidden away, and almost forgotten in a museum collection for over three decades. The findings are published in the Journal of Vertebrate Paleontology.
Jane Mansbridge, Charles F. Adams Professor in Political Leadership and Democratic Values at Harvard University, is awarded the 2018 Johan Skytte Prize in Political Science. Professor Mansbridge wins the prize for “with sharpness, deep involvement and feminist theory having shaped our understanding of democracy in its direct and representative forms.”
In a new study, published in Current Biology this week, a research team from Uppsala University reports new insights into the regenerative capabilities of Stentor, a single celled model organism for regeneration biology. The study used novel gene expression methods that allowed the researchers to identify over one thousand genes involved in the regeneration process of individual stentor cells.
Dynamic interactions between the nervous system, hormones and the immune system are normally on-going but in diabetes the balance is disturbed. The two studies published in EBioMedicine by an international research team from Uppsala University highlight the importance of the neurotransmitter gamma-aminobutyric acid (GABA) in both Type 1 and Type 2 diabetes.
Viruses have a very limited set of genes and therefore must use the cellular machineries of their hosts for most parts of their growth. A new study, led by scientists at Uppsala University, has discovered a specific host protein that many viruses use for their transport within the cell. The discovery opens up new possibilities to develop a broad spectrum anti-viral therapy.
In a multidisciplinary study published in PNAS, an international team of researchers combined archaeological, genetic and stable isotope data to encapsulate 4000 years of Iberian biomolecular prehistory.
Young digital gamers do not have fewer friends at school than their non-gamer peers, two new research articles from Uppsala University indicate.