Although some rare genetic variants can increase the risk of disease markedly for a few individuals, the genetic contribution to common diseases is mostly due to a combination of many common genetic variants with small effects. This is shown in a comprehensive study by researchers at Uppsala University and SciLifeLab, published in the journal Nature Communications.
MS patients treated with Rituximab have better responses to the COVID-19 vaccine if they have higher B cell counts. This is the finding of a study from Uppsala University published in the journal JAMA Network Open. In patients with B cell counts of 40/µL (microlitres) or more, 9 of 10 patients developed protective levels of antibodies, while significantly fewer with lower counts had similar respon
A new study from Uppsala University shows that young adults when sleep-deprived evaluate angry faces as less trustworthy and healthy-looking. Furthermore, neutral and fearful faces appear less attractive following sleep loss. The findings are published in the scientific journal Nature and Science of Sleep.
Coral species exhibit different temperature tolerances. This is in part due to the composition of their microalgae symbionts. With a new method, researchers from Uppsala University were able to predict how individual microalgae might behave under future temperature stress and identify more tolerant coral symbionts. In combination with forthcoming single cell selection and growth experiments, the
Researchers at Uppsala University have detected different subgroups of the brain tumour form glioblastoma, where the cancer cells’ properties depend on which cell type they originate from. The used analysis method could also separate glioblastoma patients with significant differences in survival. The findings open up for identifying specific therapeutic targets for the new subgroups of glioblastom
Professor Robert Goodin, Australian National University, is the recipient of the 2022 Johan Skytte Prize in Political Science. He is awarded the prize for a number of works over several decades in which he “with acuity and success endeavoured to blend political philosophy with empirical political science to increase the understanding of how decent and dignified societies can be shaped”.
In COVID Symptom Study Sweden more than 10 million daily reports from participants in COVID Symptom Study Sweden from April 2020 to February 2021. The scope of the study was to develop and evaluate a framework to estimate the regional prevalence of COVID-19 using symptom-based surveillance, and to test if these prevalence estimates could be used to predict subsequent trends in COVID-19 admissions.
A new study from scientists at Uppsala University shows that it took more than 10 millennia from when the first spruces returned to Sweden after the glacial stage of the last Ice Age until the species became widespread. This sluggish rate of initial dispersal has surprised the researchers, since the spruce might have had good prospects of expanding its range.
Immunotherapy is increasingly becoming a successful way to treat cancer. Researchers at Uppsala University have now developed armed CAR-T cells that reinforce the immune defence against cancer and that could increase the possibilities to successfully treat solid tumours. The study has been published in the journal Nature BioMedical Engineering.
Support offered by a phone app can relieve post-traumatic stress and depression. A new study from Uppsala University’s National Centre for Disaster Psychiatry involving 179 patients shows that a dedicated PTSD app, PTSD Coach, helps adults suffering from mental health issues after traumatic events.
In the condition known as cavernoma, lesions arise in a cluster of blood vessels in the brain, spinal cord or retina. Researchers at Uppsala University show in a new study that white blood cells and protein structures associated with the immune response infiltrate the vessel lesions.
Energy storage in lithium-sulfur batteries is potentially higher than in lithium-ion batteries but they are hampered by a short life. Researchers from Uppsala University in Sweden have now identified the main bottlenecks in performance.