Bacterial perseverance is a new phenomenon that helps explain how bacteria adapt to survive antibiotic treatments. A group of researchers at Uppsala University have studied how individual bacteria react when exposed to different antibiotics. The result underlines the importance of adhering strictly to antibiotic prescriptions.
A new study from researchers at Uppsala University presents novel findings on why human lymph nodes lose their function with age and the consequences for the effectiveness of our immune system. The article has been published in The Journal of Pathology.
Researchers at Uppsala University have shown that Scandinavian wolves carry around 100,000 harmful mutations in their genome. As long as the harmful mutations can be compensated by a healthy genetic variant, this does not need to pose a problem. However, as there has been a high level of inbreeding in the wolf population, the occurrence of double harmful variants has increased with each generation
Men are at an increased risk of a severe bout of COVID-19 compared to women. Researchers at Uppsala University have now shown that this may be due to loss of the Y chromosome in part of their white blood cells. The findings could eventually be used to assess the risk of developing severe COVID-19 and perhaps to improve treatment.
Using new gene mapping methods, researchers have found connections between atopic dermatitis in dogs and several regions of the genome. Some genes identified coincide with genes linked to similar problems in humans. The filaggrin gene region, for example, which is regarded as the most powerful risk factor for atopic eczema in humans, has now also been linked to this disease in Labrador retrievers.
Researchers at Uppsala University have discovered and characterised a DNA sequence found in jawed vertebrates, such as sharks and humans, but absent in jawless vertebrates, such as lampreys. This DNA is important for the shaping of the joint surfaces during embryo development.
The European robin’s closest relatives are found in tropical Africa. The European robin is therefore not closely related to the Japanese robin, despite their close similarity in appearance. This is confirmed by a new study of the Old World flycatcher family, to which these birds belong. The study comprises 92 per cent of the more than 300 species in this family.
Preschool children's play involving tablets is less creative and imaginative compared to their play involving physical toys. This is shown in a new study by Uppsala University, and the difference is substantial. The results counter occasional claims that new technology would make children more creative. Tha study is published in Learning, Media and Technology.
An team of surgeons and scientists from, among others, Uppsala University has confirmed secure surgical access to the central core of the human cochlea. The research, published in Scientific Reports, is critical to the first in-human trials of new cell, gene and drug therapies for the inner ear, and will assist with treatment for improving hearing loss and deafness over the long-term.
The malignant brain tumour type medulloblastoma can become resistant to therapy which can cause relapse. Researchers at Uppsala University have discovered a certain protein that makes tumour cells resting and insensitive to radiation treatment. The research group hopes that the results could eventually lead to better treatments for children that have the highest risk to develop relapses.
Food lies at the heart of both health and sustainable development. This year’s Uppsala Health Summit takes on the challenges associated with our food systems and how to make them healthier, more inclusive, equitable and sustainable.
Neurochemical changes in the brain differ among patients with social anxiety treated using both SSRIs and CBT, compared to those treated using only CBT. While the combined treatment involving the medicine blocked the serotonin transporters, availability of such transporters increased in patients who only received CBT. In a double-blind positron emission tomography (PET) study, 24 participants.