People with the skin condition psoriasis often have invisible inflammation in the small intestine with an increased propensity for ‘leaky gut’, according to new research at Uppsala University. These changes in the gut could explain why psoriasis sufferers often have gastrointestinal problems and are more prone to developing Crohn’s disease.
A recent study shows that the Semliki Forest virus enters the central nervous system by first entering the cerebrospinal fluid and then binding to a specific cell type before penetrating deeper into the brain. This finding could potentially be used to develop the Semliki Forest virus as an agent for treating brain cancer. The study has been published in the journal Nature Communications.
New study: An app can help parents who are mourning the loss of a child. Parents who used the app for three months reported reduced symptoms of prolonged grief and post-traumatic stress, and also had fewer negative thoughts. Some parents thought that in future, the app should be offered early in the process of mourning. The study is published in the scholarly journal Cognitive Behaviour Therapy.
Researchers have analysed the effects of seven different hormone treatments for menopausal symptoms, and the risk of blood clots, stroke and heart attack. The risks differ depending on the active substance and how the medicine is taken. The study involves around one million women aged 50-58 and is the largest and most comprehensive study of currently prescribed hormonal substances in the world.
In an international collaboration, researchers at Uppsala University have been able to identify undigested food remains, plants and prey in the fossilised faeces of dinosaurs. These analyses of hundreds of samples provide clues about the role dinosaurs played in the ecosystem around 200 million years ago. The findings have been published in the journal Nature.
Different species of seabirds can coexist on small, isolated islands despite eating the same kind of fish. A researcher at Uppsala University has been involved in developing a mathematical model that can be used to better understand how this ecosystem works.
By exploiting the genetic variation in cancer cells, an already approved cancer drug demonstrated enhanced effects against cancer cells in specific patient groups. This is shown in a recent study from Uppsala University, published in the journal eBiomedicine. The findings suggest a potential for more individually tailored and more effective cancer therapies.
Uppsala University is contributing an important piece to the puzzle of substantially shortening the radioactive life of nuclear waste. Belgian scientists aiming to create a facility to convert long-lived radioactive fuel waste into shorter-lived waste are now enlisting the help of the FREIA Laboratory in Uppsala.
Researchers at Uppsala University and KTH Royal Institute of Technology have developed a new form of precision medicine, an antibody, with the potential to treat several types of cancer. Researchers have managed to combine three different functions in the antibody, which together strongly amplify the effect of T cells on the cancer tumour. The study has been published in Nature Communications.
All patients who have had a heart attack are typically treated using beta blockers. According to a Swedish study conducted earlier this year, this drug is unlikely to be needed for those heart patients who have a normal pumping ability. Now a sub-study at Uppsala University shows that there is also a risk that these patients will become depressed by the treatment.
More children have overweight in regions with high rates of single parenthood, low education levels, low income and high child poverty. The pandemic may also have reinforced this trend. This is shown by a study conducted by researchers at Uppsala University and Region Sörmland in collaboration with Region Skåne.
Seven of the most common forest trees in Europe have been shown to be able to shelter their genetic diversity from major shifts in environmental conditions. This is despite their ranges having shrunk and the number of trees having fallen sharply during ice age cycles. These are the findings of a study jointly led by Uppsala and Helsinki Universities, published in Nature Communications.