Mutations in gene cause brain calcifications in humans and mice
Why many diseases lead to calcifications in the brain is not known. New insights into the genetic causes of familial idiopathic basal ganglia calcification (FIBGC), also referred to as Fahr’s disease, pinpoint brain pericytes and a defective blood-brain barrier (BBB) as likely culprits in brain calcification. The findings were recently published in the journal Nature Genetics.