By blocking of an enzyme that affects the cellular microenvironment it is possible to stop brain tumour cells from growing. This is shown in a new study published in the journal Molecular Cancer Therapeutics by researchers at Uppsala University in collaboration with researchers in Haifa, Israel and Brisbane, Australia.
In the latest issue of the journal Proceedings of the National Academy of Sciences (PNAS), a research group at Uppsala University presents a new, small-scale method that may become a smart shortcut for determining the “bioavailability” of a pharmaceutical drug within cells.
Specialized beta cells in the pancreas release the hormone insulin to control our blood glucose levels, and failure of this mechanism is central to the development of type-2 diabetes. How much and when insulin is released depends on a complex system of messenger molecules and proteins that is not well understood.
Time periods by calendar related to perceived stress are associated with the incidence rate of myocardial infarction (MI), says a new nationwide registry study of the Swedish population. Compared to control days, the daily incidence rate of MI was higher during the winter holidays, and on Mondays, whereas rates were lower during weekends and during the summer vacation in July.
Some insulin is still produced in almost half of the patients that have had type 1 diabetes for more than ten years. The study conducted by researchers at Uppsala University in Sweden has now been published online by the medical journal Diabetes Care.
Juvenile birds discriminate and selectively learn their own species’ songs even when primarily exposed to the songs of other species, but the underlying mechanism has remained unknown. A new study, by researchers at Uppsala University, shows that song discrimination arises due to genetic differences between species, rather than early learning or other mechanisms.
Uppsala Health Summit has decided to offer four travel grants for journalists who would not otherwise be able to attend the summit on 9–11 October 2017 at Uppsala Castle, Sweden. The theme of this year’s summit is Tackling Infectious Disease Threats: Prevent, detect, respond with a One Health approach.
Synchrotron scanning can produce high-quality 3D models of well-preserved food residues from fossil faeces. That's the result of a new study, by palaeontologists from Uppsala University and from ESRF Grenoble, which is presented in a new article in Scientific Reports.
One in five people dreams of publishing a novel. At the same time, there are no hard and fast criteria for determining whether a manuscript has the proper traits for publication by an established publisher. This creates a fundamental insecurity among both aspiring writers and publishers alike, according to a new dissertation from Uppsala University.
Why has the neoclassical Gustavian style become so prominent in the Swedish self-image? A new dissertation from Uppsala University shows how researchers in art history, along with museums, commercial enterprises and the monarchy, have contributed to preserving and conveying the Gustavian style.
Despite remarkable gains in health over the last century, infectious diseases remain a major threat. Alarming reports on outbreaks of Zika, Ebola or avian flu serve as reminders of the gravity of the situation. At the high-level meeting Uppsala Health Summit, international experts will gather from different sectors to discuss how to reduce the threats.
Epigenetic changes are chemical modifications that turn our genes off or on. In a new study from Uppsala University, researchers show that tea consumption in women leads to epigenetic changes in genes that are known to interact with cancer and estrogen metabolism. The results are published in the journal Human Molecular Genetics.