Researchers at Uppsala University have described the presence, throughout the human body, of the enzyme ACE2. This is thought to be the key protein used by the SARS-CoV-2 virus for host cell entry and development of the disease COVID-19. In contrast to previous studies, the study shows that no or very little ACE2 protein is present in the normal respiratory system.
In a new study, a research group at Uppsala University explain their outstanding success in harvesting “hot electron holes”. The results of their work can be used to improve solar cells, photochemical reactions and photosensors. The scientific article is published in Nature Materials.
Therapies for treating glioblastoma brain cancer can be delivered with greater precision and existing drugs can be used in new ways. These are the conclusions from a study from Uppsala University investigating a large number of cell samples from patients with brain tumours. The researchers have characterised how changes in glioblastoma cells influence the effect of different drugs.
The evolution of our teeth began among ancient armoured fishes more than 400 million years ago. In the scientific journal Science, an international team led by researchers from Uppsala University presents ground-breaking findings about these earliest jawed vertebrates. Using powerful X-ray imaging, they show that unique fossils found near Prague contain surprisingly modern-looking teeth.
Characteristics of palm trees differ from those of other tropical trees in many ways. In a major new study led by scientists at Uppsala University, Sweden, and University of Campinas, Brazil, they have surveyed the actual numbers of palms in tropical rainforests around the globe.
A new mathematical model for predicting variations in solar irradiance has been developed at Uppsala University. It may help to promote more efficient use of electricity from solar energy. In tests of various data models, the model proved capable of making highly reliable forecasts, and emerged as the best for this purpose in some respects.
Scientists at Uppsala University have discovered a hitherto unknown function of blood platelets in cancer. In mouse models, these platelets have proved to help preserve the vascular barrier which makes blood-vessel walls selectively impermeable, thereby reducing the spread of tumour cells to other parts of the body. The study is published in the journal Cancer Research.
Life depends on an intricate game of hide-and-seek taking place inside the cell. New research, which is now published in the journal Nature, sheds light on the mechanisms with which DNA-binding proteins search the genome for their specific binding sites.
Many pharmaceuticals work by targeting what are known as “G-protein-coupled receptors”. In a new study, scientists from Uppsala University describe how they have been able to predict how special molecules that can be used in new immunotherapy against cancer bind to these receptors.
New data from the Uppsala Conflict Data Program (UCDP), Uppsala University, shows that the number of fatalities in organised violence continues to decrease. The declared defeat of Islamic State (IS) in Syria and Iraq has pushed the number of fatalities to its lowest level since the outbreak of the Syrian civil war in 2011. However, peace researchers are worried about recent trends in Africa.
A research team at Uppsala University has resurrected several billion-year-old enzymes and reprogrammed them to catalyse completely different chemical reactions than their modern versions can manage. The method can be used to develop sustainable solutions within biotechnology, such as for enzyme bioreactors or to chemically degrade environmental toxins.
Researchers at Uppsala University have developed a method for identifying functional mutations and their effect on genes relevant to the development of glioblastoma – a malignant brain tumour with a very poor prognosis. The study is published in Genome Biology.
