Uppsala University scientists have designed a new mouse model that facilitates study of factors contributing to the progression of human bladder cancer and of immune-system activation when the tumour is growing. Using this model, they have been able to study how proteins change before, while and after a tumour develops in the bladder wall. The study has now been published in PLOS ONE.
The Swedish Government was able to undertake and justify Swedish military involvement in Afghanistan 2002–2014 by describing it as a traditional Swedish contribution while differentiating it from American military operations in the region. Both consensus and a sense of continuity in foreign policy formulation are required to achieve broad support, finds a new dissertation from Uppsala University.
Uppsala University has appointed Cecilia Wikström to chair the governing board of the University’s new knowledge centre for nuclear disarmament and Professor Erik Melander to be the centre’s director. Following these appointments, the Alva Myrdal Centre can start its activities.
Researchers have successfully sequenced the entire genome from the skull of Peştera Muierii 1, a woman who lived 35,000 years ago. Her high genetic diversity shows that the out-of-Africa migration was not the great bottleneck in human development but rather this occurred during and after the most recent Ice Age. This new study, led by Professor Mattias Jakobsson, is published in Current Biology.
When the first descriptions of knitting and crochet were published in Swedish, in the mid-19th century, such handiwork was described as the finest of all feminine handicrafts, for the benefit and pleasure alike of the trend-conscious, middle- and upper-class woman. Within a few decades, the patterns had moved into fashion journals. A new thesis examines how these changes affected handicrafts.
A comprehensive study from Uppsala University demonstrates that socioeconomic deprivation modifies genetic effects on higher education and abstract reasoning. The paper illustrates how genes play a greater role in educational attainment in more socioeconomically deprived regions of the United Kingdom. The study was recently published in the American Journal of Psychiatry.
Over 50 millennia, at least five major immigration waves have successively populated the Philippines, the most comprehensive survey of genetic variations in the country to date shows. This Uppsala University study, published in the scientific journal PNAS, comprises 2.3 million DNA markers from some 1,000 individuals.
Mutations in the neurochondrin (NCDN) gene can cause epilepsy, neurodevelopmental delay and intellectual disability. The gene mutation significantly impairs contacts and signalling between neurons in the brain. This is the conclusion of a study led from Uppsala University and published in the American Journal of Human Genetics.
Researchers at Uppsala University have developed a digital self-test that trains users to assess news items, images and videos presented on social media. The self-test has also been evaluated in a scientific study, which confirmed the researchers’ hypothesis that the tool genuinely improved the students’ ability to apply critical thinking to digital sources.
The effects of the endocrine disruptor linuron on frogs are not limited to those exposed, but are passed on to their offspring (reduced body weight and decreased fertility) and grand-offspring (increased body weight and a disrupted metabolism). This is demonstrated by a new study (Uppsala University and Stockholm University), published in the journal Science of the Total Environment.
Hydrogen for energy use can be extracted in an environmentally friendly way from water and sunlight, using photocatalytic composite polymer nanoparticles developed by researchers at Uppsala University. In laboratory tests, these “polymer dots” showed promising performance and stability alike. The study has been published in the Journal of the American Chemical Society.
Stefania Barca, from the University of Coimbra in Portugal, is to be Uppsala University’s fourth Zennström Professor of Climate Change Leadership. In her research, she focuses particularly on issues of justice connected with environmental and climate change.
Uppsala University has joined the Leap Health Breakthrough Network, a global group of 21 leading academic and research institutions committed to solving the world’s most serious health challenges — such as cancer and infectious diseases — at record speed. Wellcome Leap is a US-based non-profit organisation founded by the Wellcome Trust to accelerate innovations that benefit global health.
An adverse upbringing often impairs people’s circumstances and health in their adult years, especially for couples who have both had similar experiences. This is shown by a new study, carried out by Uppsala University researchers, in which 818 mothers and their partners filled in a questionnaire one year after having a child together. The study is now published in the scientific journal PLOS ONE.
Until now, the reason why the drug levodopa (L-Dopa), which reduces the motor symptoms of Parkinson’s disease, declines in efficacy after a few years’ use has been unknown. A side effect that then often occur is involuntary movements. A Swedish–French collaboration, led from Uppsala University, has now been able to connect the problems with defective metabolism of L-Dopa in the brain.
Today, the Swedish Government decided to assign to Uppsala University the task of setting up a new national knowledge centre for research on nuclear disarmament. With an interdisciplinary approach and researchers in fields including peace and conflict research and nuclear physics, the incipient Alva Myrdal Centre will conduct research with the goal of contributing to a safer world for humankind.
The Order of Freemasons’ meticulous archives are fundamental to their identity. The unique structure of the masonic archives reinforces the secrecy and mystique of the self-image that has been fashioned by the Order — and characterises it in the eyes of others. This is shown in a recent thesis from Uppsala University, which focuses on the Masons’ archives in the 18th and 19th centuries.
You might need a microscope to witness the next agricultural revolution. New research, published in the journal Science Advances, demonstrates how microfluidic technologies can be used to identify, isolate and propagate specific single photosynthetically active cells for fundamental industry applications and improved ecosystem understanding.
Researchers have discovered a new group of Chlamydiae, Anoxychlamydiales, living under the ocean floor without oxygen. These have genes that allow them to survive without oxygen while making hydrogen gas. The researchers found that our single-cell ancestors ‘caught’ these hydrogen-producing genes from ancient Chlamydiae up to two-billion years ago – The results are published in Science Advances.
Scientists at Uppsala University have discovered a hitherto unknown function of blood platelets in cancer. In mouse models, these platelets have proved to help preserve the vascular barrier which makes blood-vessel walls selectively impermeable, thereby reducing the spread of tumour cells to other parts of the body. The study is published in the journal Cancer Research.
