IgA deficiency is one of the most common genetic immunodeficiency disorders in humans and is associated with an insufficiency or complete absence of the antibody IgA. Researchers from Uppsala University and Karolinska Institutet have now performed the first comparative genetic study of IgA deficiency by using the dog as genetic disease model. The results are published in PLOS ONE.
New research from Uppsala University shows promising progress in the use of anti-inflammatory cytokine for treatment of type 1 diabetes. The study, published in the open access journal Scientific Reports, reveals that administration of interleukin-35 to mice with type 1 diabetes, reverses or cures the disease by maintaining a normal blood glucose level and the immune tolerance.
It is known that sleep facilitates the formation of long-term memory in humans. In a new study, researchers from Uppsala University now show that sleep does not only help form long-term memory but also ensures access to it during times of cognitive stress.
A new technique to study proteins, which does not require advanced equipment, specialized labs or expensive reagents, has been developed at Uppsala University, Sweden. The technique could be further developed to be used in point of care devices, for instance for diagnostic purposes.
New research from Uppsala University shows promising progress in the use of stem cells for treatment of spinal cord injury. The results, which are published in the scientific journal Scientific Reports, show that human stem cells that are transplanted to the injured spinal cord contribute to restoration of some sensory functions.
Researchers from Uppsala University have studied the risk of dying over the next five years. They have developed a unique health-risk calculator by using one of the world’s largest study material, UK Biobank, containing data from nearly half a million people. The results are expected to have large areas of application both in the clinical setting, public health policy and in research.
An Uppsala Antibiotics Centre is to be created at Uppsala University. This was announced by Deputy Vice-Chancellor Anders Malmberg at today’s opening of the Uppsala Health Summit conference. The goal is for this interdisciplinary centre to be a regional, national and international knowledge resource and forum in the area of antibiotic resistance.
The importance of the umbilical cord not only for the foetus but for newborn infants too has been shown by Swedish researchers a few years ago. In a follow-up study in the journal JAMA Pediatrics they have now been able to show an association between delayed cord clamping (DCC) and children’s fine motor skills at the age of four years, especially in boys.
In a study published this month in Malaria Journal, researchers from Uppsala University and other institutions present a new model for systematically evaluating new malaria treatment programs in routine conditions across multiple countries.
Researchers at Uppsala University have, together with researchers from Turku and Bergen, discovered a new biomarker which makes it possible to identify women with uterine cancer who have a high risk of recurrence. The findings were recently published in the journal Gynecologic Oncology.
The theme for the next Uppsala Health Summit, to be held in Uppsala, Sweden, on 2–3 June 2015, is antibiotic resistance — one of the biggest global health challenges of our day. The basis of the Summit will be the WHO draft Global Action Plan against antimicrobial resistance that is the focus for the high-level meeting starting today in Stockholm, hosted by the Public Health Agency of Sweden.
Scientists from Uppsala University, the Science for Life Laboratory (SciLifeLab) in Stockholm and Uppsala University Hospital have developed a new method of rapidly identifying which bacteria are causing an infection and determining whether they are resistant or sensitive to antibiotics. The findings are now being published in the Journal of Clinical Microbiology.
In a new study published in the scientific journal Oncotarget researchers from Uppsala University show that a therapeutic vaccine directed against tumor vessels can reduce tumor burden and suppress formation of spontaneous lung metastases in a mouse model for metastatic breast cancer.
If chronic lymphocytic leukemia patients with a good or poor prognosis could be identified already at the time of diagnosis, physicians would have better possibilities to adjust their therapeutic and follow-up strategies. Now researchers at Uppsala University have discovered a new correlation between specific molecular features of the disease and subgroups of patients with different prognosis.
Different types of glioma are usually diagnosed as separate diseases and have been considered to arise from different cell types in the brain. Now researchers at Uppsala University have shown that one and the same cell of origin can give rise to different types of glioma.
What does it mean to simulate the human brain? Why is it important to do so? And is it even possible to simulate the brain separately from the body it exists in? These questions are discussed in a new paper published in the scientific journal Neuron today.
A new Swedish study shows that adolescents who suffer from sleep disturbance or habitual short sleep duration are less likely to succeed academically compared to those who enjoy a good night’s sleep. The results have recently been published in the journal Sleep Medicine.
In a new study published in Nature Communications, research scientists from Uppsala University present for the first time a large-scale study of the significance of genetic, clinical and lifestyle factors for protein levels in the bloodstream. The results of the study show that genetics and lifestyle are determining factors for protein levels.
More than 80 percent of all drug candidates in the pharma R&D suffer from poor solubility and are therefore rejected early in the drug discovery process. Now Uppsala University researchers show that the new material Upsalite®, has great potential for development of new formulations of these rejected drugs.
In a new study published today in the journal Plos One, researchers at Uppsala University show that the harmful effect of smoking is aggravated if the person has high blood levels of PCB. This indicates that environmental contaminants interact with other risk factors for various diseases – a field the researchers claim is under-researched.