Selective serotonin reuptake inhibitors (SSRIs) are commonly prescribed for depression and anxiety but their superiority over placebo has been questioned, generating considerable debate among researchers and clinicians. In a new study, Uppsala University researchers show that the way in which the treatment is described to the patient can be as important as the treatment itself.
The patient perspective is important in all medical research, and particularly in drug development. This month, a public private research initiative called PREFER, is launched to assess when and how patient preferences on benefits and risks should be incorporated in decisions on medicinal products
For the first time, researchers have revealed the nanostructure of the mesoporous magnesium carbonate Upsalite® and pore size control was achieved without organic templates or swelling agents. By controlling the pore structure of the material the amorphous phase stabilisation exerted on poorly soluble drug compounds can be tuned and the drug delivery rate can be tailored.
For the first time, researchers have succeeded in passing an antibody through the blood-brain barrier to act as a tracer for PET imaging of the brain. This resulted in more precise information being obtained than with regular radioactive tracers. The study provides hope for more effective diagnosis of early onset Alzheimer’s disease and improvements in monitoring the effects of medication.
A new smart research robot accelerates research on cancer treatments. The new robot system finds optimal treatment combinations. Today Scientific Reports (Nature Publishing Group) is publishing an article about the robot, authored by Dr Mats Gustafsson, Professor of Medical Bioinformatics at Uppsala University.
For the upcoming Uppsala Health Summit on antibiotic resistance, 2–3 June, a report has now been published focusing on some of the most pressing issues and challenges. The aim of the meeting is to move the discussion forward, from the ‘what’ to the ‘who’ and ‘how’.
Shortly after the World Health Organization (WHO) global action plan on antibiotic resistance has been adopted in May 2015, researchers, politicians and representatives from public health organizations and the pharmaceutical industry will gather in Uppsala, Sweden, to discuss the most urgent next steps.
A new study from Uppsala University demonstrates that elderly humans carrying a common variant of the fat mass and obesity gene FTO also have a shifted endocrine balance. Low blood concentrations of the satiety hormone leptin and high blood concentrations of the hunger promoting hormone ghrelin makes carriers of the FTO gene put on weight. The findings are published in the journal Diabetes.