A new study from Uppsala University demonstrates that elderly humans carrying a common variant of the fat mass and obesity gene FTO also have a shifted endocrine balance. Low blood concentrations of the satiety hormone leptin and high blood concentrations of the hunger promoting hormone ghrelin makes carriers of the FTO gene put on weight. The findings are published in the journal Diabetes.
In a new study, published in Nature Communications today, researchers from the Department of Medical Cell Biology at Uppsala University describe findings that offer new clues as to why insulin secretion might fail in diabetes and open the possibility of discovering novel drugs.
In a new study published today in the journal Plos One, researchers at Uppsala University show that the harmful effect of smoking is aggravated if the person has high blood levels of PCB. This indicates that environmental contaminants interact with other risk factors for various diseases – a field the researchers claim is under-researched.
Get set for 3-4 June: Uppsala University and seven other Swedish actors, has invited politicians, opinion-makers and experts from healthcare, academia and companies to an unconditional and open dialogue on the ways forward in an ageing society. The goal of the Uppsala Health Summit is to move from knowledge to action.
It is generally well known that men have an overall shorter life expectancy compared to women. A recent study, led by Uppsala University researchers, shows a correlation between a loss of the Y chromosome in blood cells and both a shorter life span and higher mortality from cancer in other organs.
Using computer simulations to predict which drug candidates offer the greatest potential has thus far not been very reliable, because both small drug-like molecules and the amino acids of proteins vary so much in their chemistry. Uppsala researchers have now cunningly managed to develop a method that has proven to be precise, reliable and general.
Researchers at the Division of Nanotechnology and Functional Materials, Uppsala University have developed a paper filter, which can remove virus particles with the efficiency matching that of the best industrial virus filters. The paper filter consists of 100 percent high purity cellulose nanofibers, directly derived from nature.
A research group at Uppsala University, Sweden has developed a new responsive coating for implants used in surgery to improve their integration into bone and to prevent rejection. Neutron scattering experiments at the Institut Laue-Langevin (ILL) in Grenoble, France have shown how a protein that promotes bone growth binds to this surface and can be released in a controlled way.
When tumours grow, new blood vessels are formed that deliver oxygen and nutrients to the tumour cells. A research group at Uppsala University has discovered a new type of cell communication that results in suppressed blood vessel formation and delayed tumour growth.
The growing problem of resistance to antibiotics is very costly, both in human lives and in resources. Uppsala University is now to be a leading actor in a gigantic EU-funded project in which academia, the pharmaceutical industry and the biotechnology industry will collaborate to fast-track the development of new antibiotics.
Ancient DNA from early Iberian farmers shows that the wideheld evolutionary hypothesis of calcium absorption was not the only reason Europeans evolved milk tolerance.
A new study from Uppsala University, Sweden, shows that one night of sleep deprivation increases morning blood concentrations of NSE and S-100B in healthy young men. These molecules are typically found in the brain. Thus, their rise in blood after sleep loss may indicate that a lack of snoozing might be conducive to a loss of brain tissue. The findings are published in the journal SLEEP.
The fact that smoking means a considerable health risk is nowadays commonly accepted. New research findings from Uppsala University and Uppsala Clinical Research Center show that smoking alters several genes that can be associated with health problems for smokers, such as increased risk for cancer and diabetes.
Perfluorinated compounds are environmental toxins that are found in fire extinguishing foam and water-repellent textiles and, for example. In a new study, a research team led from Uppsala University has seen links between high levels of perfluorinated compounds in the blood and diabetes.
Bone cancer in dogs is affected by a variety of genetic risk factors. Researchers from Uppsala University and the Broad Institute show this in a new study published in Genome Biology.
A research study from Uppsala University, Sweden, is now presenting a model of how bacteria can rapidly adapt to environmental changes through smart regulation of their gene expression. This is important not least for our understanding of resistance to antibiotics.
Retroviruses are important pathogens capable of crossing species barriers to infect new hosts, but knowledge of their evolutionary history is limited. By mapping endogenous retroviruses (ERVs), researchers at Uppsala University, Sweden, can now provide unique insights into the evolutionary relationships of retroviruses and their host species.
It was previously thought that the two test methods signalled the same type of asthma. But a new study, led by researchers at Uppsala University, Sweden, shows that the methods actually signal two different inflammatory processes. With the tests used in combination, the chances are probably greater for the patient to receive just the right treatment.
Rape in war cannot be addressed in isolation. It is deeply embedded in both the local context and that of global proportions. This is one of the conclusions made in a doctoral thesis about eastern Democratic Republic of Congo presented at Uppsala University on 19th September.
In the event of cardiac arrest outside of a hospital it is important to provide effective chest compressions without interruption. Creating blood flow reduces the risk of brain damage and improves the chances of survival. A new Swedish study shows that mechanical treatment yields results that are at least as good as manual treatment.