Organoid

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Organoid

The picture shows how Shigella bacteria (green) spread over time in a lab-grown miniature intestine.
Maria Letizia Di Martino
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Maria Letizia Di Martino
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.jpg
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6000 x 1826, 1.33 MB
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  • "For the first time we have been able to map the genes Shigella needs to cause infection using a human model that mimics intestinal tissue," says Maria Letizia Di Martino, one of the study’s lead authors. Photo: Mikael Wallerstedt

    Cultured mini-organs reveal the weapons of aggressive bacteria

    Thanks to lab-grown miniature intestines, researchers at Uppsala University have successfully mapped how aggressive Shigella bacteria infect the human gut. The study opens the door to using cultured human mini-organs to investigate a wide range of other serious infections.

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