Researchers at Uppsala University and Uppsala University Hospital have developed a new method to measure levels of the medication hydroxychloroquine in patients with the rheumatic disease systemic lupus erythematosus (SLE). The analysis method may also be useful in other areas, such as in the treatment of COVID-19. The study is being published in Arthritis Research and Therapy.
Enzymes from cold-loving organisms that live at low temperatures, close to the freezing point of water, display highly distinctive properties. In a new study published in Nature Communications, scientists at Uppsala University have used large-scale computations to explain why many cold-adapted enzymes stop functioning at around room temperature.
The organ of balance in the inner ear is surrounded by the hardest bone in the body. Using synchrotron X-rays, researchers at Uppsala University have discovered a drainage system that may be assumed to play a major role in the onset of Ménière's disease, a common and troublesome disorder. These results are published in the journal Scientific Reports.
Without a wife and a well-functioning household, Carl Linnaeus would have had difficulty becoming the prominent scientist that he was. Mastering social codes, like clothing and hosting guests for dinners, was crucial for having a career in the 18th century. These are the conclusions of a recently defended thesis at Uppsala University.
Patients taking part in clinical trials do not receive better treatment than other patients. This is the conclusion of a new study led from Uppsala University and published in peer-reviewed journal BMC Cancer, which confirms the results of an earlier study from 2004.
Despite the traditional view that species do not exchange genes by hybridisation, recent studies show that gene flow between closely related species is more common than previously thought. A team of scientists from Uppsala University and Princeton University now reports how gene flow between two species of Darwin’s finches has affected their beak morphology.
Artificial intelligence (AI) may be an aid to interpreting ECG results, helping healthcare staff to diagnose diseases that affect the heart. Researchers at Uppsala University and heart specialists in Brazil have developed an AI that automatically diagnoses atrial fibrillation and five other common ECG abnormalities just as well as a cardiologist.
In an international collaboration, researchers from Uppsala University have mapped the lymph node lymphatic vessels in mice and humans down to the level of individual cells. The results may eventually help scientists to discover new methods for strengthening the immune system against viruses and cancer. Their work has been published in the journal Frontiers of Cardiovascular Research.
Individuals with social anxiety disorder have markedly different personality traits than others. Emotional instability and introversion are hallmarks, according to a new study from Uppsala University published in PLOS ONE.
Under the volcanoes in the Central Andes there is a gigantic reservoir of molten magma. For several million years, it has been there without fully solidifying or causing a supervolcanic eruption. Geologists have long wondered how this is possible. Researchers from Uppsala University, among others, have now discovered that the secret may be hidden tributaries of hot magma from inside the Earth.
Patients with type 2 diabetes secrete not only too little insulin but also too much glucagon, which contributes to poor blood glucose control. A new study from Uppsala University suggests that this is because the glucagon-secreting α-cells have become resistant to insulin.
Peter J. Katzenstein, Cornell University, USA, has been named the 26th recipient of the Johan Skytte Prize in Political Science. He is awarded the prize for “furthering the understanding of how history, culture, and norms shape economies, as well as national and global security policy”.