Researchers at Uppsala University, Stockholm University and KTH have managed to create a new spatial omics method. By combining two complex techniques that are usually used separately – mass spectrometry imaging (MSI) and spatially resolved transcriptomics (SRT) – they have taken an important step in research on biological tissues. The study is published in the Nature Biotechnology.
An international research consortium has generated and analysed 2000 canine genomes. The resulting advanced genetics toolkit can now be used to answer complex biological questions, spanning dog domestication, genetic differences in breed morphology, behaviour and disease susceptibility, as well as the evolution and structure of the genome.
A new DNA study has nuanced the picture of how different groups intermingled during the European Stone Age, but also how certain groups of people were actually isolated. The study was carried out by researchers at Uppsala University working with an international team of researchers, who produced new genetic data from 56 Central and Eastern European individuals from the Stone Age.
Researchers at Uppsala university have developed a new method to find mutations in brain tumors in children. They could also show that the mutations identified by them changes how cancer cells respond to a cancer drug. These findings could lead to better diagnostics and more individualized treatment of children with brain tumors. The study is published in the journal PNAS.
In a major Swedish study, researchers have discovered a link between the levels of certain bacteria living in the gut and coronary atherosclerotic plaques. Such atherosclerotic plaques constitute a major cause of heart attacks. The study was led by researchers at Uppsala University and Lund University and the findings have now been published in the scientific journal Circulation.
For the first time, researchers have succeeded in predicting how to change the optimum temperature of an enzyme using large computer calculations. A cold-adapted enzyme from an Antarctic bacterium was used as a basis. The study is to be published in the journal Science Advances and is a collaboration between researchers at Uppsala University and the University of Tromsø.
A new study by Uppsala University shows that a higher body mass index (BMI) increases the risk of five different rheumatic diseases: rheumatism, osteoarthritis, gout, psoriatic arthritis and inflammatory spondylitis. The researchers also noted that BMI was a stronger risk factor for women compared to men in terms of gout and psoriatic arthritis. The study will be presented in the journal Arthritis
It was the inability of both the political right and left to see and take responsibility for the systemic failures of the welfare society that led to the so-called “begging debate” in the early 2010s. This inability meant that they gave a free pass to the Sweden Democrats, who were alone able to formulate both the problem and their solution.These are some of the conclusions in a new monograph.
Many studies have linked obesity to an increased risk of cancer, but most have not differentiated the risks between men and women. In a new study published in Cancer Cell, researchers from Uppsala University takes a closer look at this connection.
Women who used combined contraceptive pills were at greater risk of developing depression than women who did not, according to a new study. The pills increased women’s risk by 73 per cent during the first two years of use. “Since we only investigated combined contraceptive pills in this study, we cannot draw conclusions about other contraceptive options", says leading researcher Uppsala University
A genomic analysis of ancient human remains from Morocco in northwest Africa revealed that food production was introduced by Neolithic European and Levantine migrants and then adopted by local groups. A research team from Sweden, Spain and Morocco present their results in Nature on June 7th.
At least 237,000 people died in organised violence in 2022. A new report from UCDP at Uppsala University shows that this is a 97 per cent increase compared with the previous year, and the highest number since 1994. UCDP is the world’s main provider of data on organised violence. Its definition of armed conflict has become the global standard of how conflicts are systematically defined and studied