A recent study shows that the Semliki Forest virus enters the central nervous system by first entering the cerebrospinal fluid and then binding to a specific cell type before penetrating deeper into the brain. This finding could potentially be used to develop the Semliki Forest virus as an agent for treating brain cancer. The study has been published in the journal Nature Communications.
New study: An app can help parents who are mourning the loss of a child. Parents who used the app for three months reported reduced symptoms of prolonged grief and post-traumatic stress, and also had fewer negative thoughts. Some parents thought that in future, the app should be offered early in the process of mourning. The study is published in the scholarly journal Cognitive Behaviour Therapy.
Researchers have analysed the effects of seven different hormone treatments for menopausal symptoms, and the risk of blood clots, stroke and heart attack. The risks differ depending on the active substance and how the medicine is taken. The study involves around one million women aged 50-58 and is the largest and most comprehensive study of currently prescribed hormonal substances in the world.
Researchers at Uppsala University and KTH Royal Institute of Technology have developed a new form of precision medicine, an antibody, with the potential to treat several types of cancer. Researchers have managed to combine three different functions in the antibody, which together strongly amplify the effect of T cells on the cancer tumour. The study has been published in Nature Communications.
A survey led by researchers at Uppsala University in Sweden reveals that a significant proportion of UK general practitioners (GPs) are integrating generative AI tools, such as ChatGPT, into their clinical workflows. The results highlight the rapidly growing role of artificial intelligence in healthcare – a development that has the potential to revolutionise patient care but also raises concerns.
Researchers at Uppsala University Hospital and Uppsala University have demonstrated that a simple blood test that reflects brain health can predict which people are most at risk of suffering a stroke. The discovery could contribute to more individualised treatment of patients with atrial fibrillation. The study has been published in the journal Circulation.
Using a unique collection of genetic and clinical data for colorectal cancer, researchers at Uppsala University have revealed genetic new alterations and developed of a new molecular classifier of tumour variants. The finding could lead to improved possibilities for individualised therapies. This is shown in study recently published in the journal Nature.
Scientists at Uppsala University have discovered a new class of antibiotics with potent activity against multi-drug resistant bacteria, and have shown that it cures bloodstream infections in mice. The new antibiotic class is described in an article in the scientific journal PNAS.
Researchers have discovered that bank voles in Skåne, southern Sweden, carry a virus that can cause hemorrhagic fever in humans. This finding was made more than 500 km south of the previously known range. This is revealed in a new study from Uppsala University. The researchers were surprised that such a high proportion of the relatively few voles they caught were actually carrying a hantavirus.
Women with a type of ovarian cancer known as germ cell tumours have a worse prognosis than men with similar tumours, i.e. testicular cancer. After five years with the disease, 98 percent of men were alive while the survival rate for women was only 85 percent. This has been revealed by a new study from Uppsala University and Uppsala University Hospital published in the Journal of Internal Medicine.
The most important support person for women to succeed in their ambition to breastfeed is the new mother’s partner. The partner also needs to be included through more support from healthcare professionals. For single mothers, alternative solutions must be found. “Single people are a vulnerable group and need other types of support," explains researcher Ingrid Blixt.
The number of infections by the tick-borne TBE virus that are not detected by health services is far higher than previously assumed. This has been shown in a new study of Swedish blood donors from Uppsala University and the University Hospital in Uppsala. The results have been published in the journal Eurosurveillance, which is associated with the EU’s Centre for Disease Prevention and Control.
Researchers at Uppsala University have developed an instrument that makes it possible to measure 21 biomarkers for cardiovascular disease simultaneously with great precision by means of a simple blood test. The aim is to use this type of tool to improve the prediction of cardiovascular complications and facilitate more personalised treatment for patients.
The nuclear accident in Chernobyl in 1986 led to the spread of radioactivity across Sweden and Europe. In a long-term study now published in Environmental Epidemiology, researchers have used new, more specific calculation methods to show the connection between radiation dose and certain types of cancer.
Researchers have identified a new neural circuit in the brain which produces a strong sense of discomfort when activated. The discovery also allows them to show for the first time that the subthalamic nucleus, a structure in the brain that controls voluntary movements, may also play a role in the development of depression. The results could lead to better treatments for Parkinson's disease.
Young children are able to talk in detail about their feelings and how things are at home. They are also good at reading their parents and their emotions by describing their behaviours, facial expressions and tone of voice. This has been shown in a new study by Uppsala University, published in the Journal of Child and Family Studies.
Women with a high genetic predisposition for blood clots are six times more likely to develop a blood clot during the first two years of using contraceptive pills according to a new study from Uppsala University. The results have been published in the American Journal of Obstetrics and Gynaecology.
Contraceptive pills can reduce the risk of rheumatoid arthritis, while hormone treatment in connection with menopause can increase the risk later in life. In a new study of more than 200,000 women in the UK, researchers at Uppsala University have discovered connections between the use of sex hormones and the risk of developing rheumatoid arthritis.
Survival rates for men with metastatic prostate cancer have increased by an average of six months, something which coincides with the gradual introduction of ‘dual treatment’ since 2016. This is according to a register study of all Swedish men diagnosed between 2008 and 2020. The results are published in the medical journal JAMA Network open.
Researchers from Uppsala University have revealed one of the mechanisms behind the growth of cancer cells in the blood cancer multiple myeloma. The study shows that the protein EZH2 interacts with a specific RNA molecule to block genes that are important for tumour growth. The findings might contribute to the development of new treatments for multiple myeloma patients.
Founded in 1477, Uppsala University is the oldest university in Sweden. With more than 50,000 students and 7,500 employees in Uppsala and Visby, we are a broad university with research in social sciences, humanities, technology, natural sciences, medicine and pharmacology. Our mission is to conduct education and research of the highest quality and relevance to society on a long-term basis. Uppsala University is regularly ranked among the world’s top universities.
Dag Hammarskjölds väg 7
BOX 256, 751 05 Uppsala
Sweden