A recent study shows that the Semliki Forest virus enters the central nervous system by first entering the cerebrospinal fluid and then binding to a specific cell type before penetrating deeper into the brain. This finding could potentially be used to develop the Semliki Forest virus as an agent for treating brain cancer. The study has been published in the journal Nature Communications.
Animals bred in the fur animal industry can both carry and spread viruses with the potential to infect humans. In a new study conducted by researchers at Uppsala University and others, researchers have identified 36 previously unknown viruses. The study has been published in the journal Nature.
Researchers have discovered that bank voles in Skåne, southern Sweden, carry a virus that can cause hemorrhagic fever in humans. This finding was made more than 500 km south of the previously known range. This is revealed in a new study from Uppsala University. The researchers were surprised that such a high proportion of the relatively few voles they caught were actually carrying a hantavirus.
People who have had the herpes virus at some point in their lives are twice as likely to develop dementia compared to those who have never been infected. A new study from Uppsala University confirms previous research on whether herpes can be a possible risk factor for dementia.
The number of infections by the tick-borne TBE virus that are not detected by health services is far higher than previously assumed. This has been shown in a new study of Swedish blood donors from Uppsala University and the University Hospital in Uppsala. The results have been published in the journal Eurosurveillance, which is associated with the EU’s Centre for Disease Prevention and Control.
There was a significant difference in the speed with which different groups were vaccinated against COVID-19. One explanation could be that people absorb information and make decisions in different ways. A new study shows that among people with the highest cognitive ability, 80% had been vaccinated within 50 days. Among those with the lowest cognitive ability, it took 180 days to achieve the same
Researchers from Uppsala University have developed a method that helps immune cells exit from blood vessels into the tumour and kill cancer cells. The aim is to improve treatment of aggressive brain tumours. The study has been published in the journal Cancer Cell.
One strategy that viruses use to take over a host cell is to mimic small parts of the cell's proteins called motifs. In a new study coordinated from Uppsala University, researchers have used a new method and doubled the available information on how viruses mimic human binding motifs. The results suggest new targets for the development of antiviral inhibitors.
Overweight and obesity among four-year-olds increased during the COVID-19 pandemic, according to a new study by Uppsala University involving over 200,000 children in Sweden. The number of children with obesity increased by some 30 percent, and there are large regional differences. The study was published in the journal Acta Paediatrica.
Detailed images of illness, death and cancelled activities; these were some of the common themes of children’s drawings during the COVID-19 pandemic. A new study from Uppsala University, in which researchers studied 91 drawings made by children aged between 4 and 6, shows that the pandemic affected the children significantly and that they had extensive knowledge about the disease.
The use of broad-spectrum antibiotics increased drastically in intensive care at the beginning of the Covid-19 pandemic. At first, this helped patients and seemed to prevent the growth of most bacteria. However, it also contributed to a sharp growth in enterococci, an antibiotic-tolerant group of bacteria, which rendered the treatment of urinary tract infections more difficult.
Men are at an increased risk of a severe bout of COVID-19 compared to women. Researchers at Uppsala University have now shown that this may be due to loss of the Y chromosome in part of their white blood cells. The findings could eventually be used to assess the risk of developing severe COVID-19 and perhaps to improve treatment.
Historic virus infections can be traced in vertebrate genomes. For millions of years, these genomes have been repositories for retroviruses that incorporated their code into germline cells and were inherited as endogenous retroviruses (ERVs). Researchers from Uppsala University now provide new findings about retroviral establishment in the koala genome. The findings are being published in PNAS.
Researchers from the Zoonosis Science Center at Uppsala University have identified a new coronavirus. Their study of approximately 260 bank voles caught around Grimsö, Örebro County, shows that the virus is well established in Sweden’s red-backed voles. The finding has been published in the journal Viruses.
A gene variant in the natural immune system influences the risk for blood clots in the lungs of severely ill COVID-19 patients. This has been documented in a new study by researchers at Uppsala University and Karolinska Institutet that has now been published in Nature Immunology.
MS patients treated with Rituximab have better responses to the COVID-19 vaccine if they have higher B cell counts. This is the finding of a study from Uppsala University published in the journal JAMA Network Open. In patients with B cell counts of 40/µL (microlitres) or more, 9 of 10 patients developed protective levels of antibodies, while significantly fewer with lower counts had similar respon
In COVID Symptom Study Sweden more than 10 million daily reports from participants in COVID Symptom Study Sweden from April 2020 to February 2021. The scope of the study was to develop and evaluate a framework to estimate the regional prevalence of COVID-19 using symptom-based surveillance, and to test if these prevalence estimates could be used to predict subsequent trends in COVID-19 admissions.
Founded in 1477, Uppsala University is the oldest university in Sweden. With more than 50,000 students and 7,500 employees in Uppsala and Visby, we are a broad university with research in social sciences, humanities, technology, natural sciences, medicine and pharmacology. Our mission is to conduct education and research of the highest quality and relevance to society on a long-term basis. Uppsala University is regularly ranked among the world’s top universities.
Dag Hammarskjölds väg 7
BOX 256, 751 05 Uppsala
Sweden