Women who have been exposed to multiple traumatic experiences during childhood have more difficult births than others. They are much more likely to need emergency caesarean sections, suffer major haemorrhages or pre-eclampsia, and need more antibiotics. These findings come from a new study involving 1,253 women, who were monitored from before giving birth to one year afterwards.
The Director-General of the World Health Organisation, Dr Tedros Adhanom Ghebreyesus, will give an open lecture in Uppsala on Friday 28 November. The title of the lecture is “Multilateralism, Health and Peace: Past Achievements, Present Difficulties, Future Hope”. The lecture is open to the public and will be followed by a panel discussion.
The malignant pediatric brain tumor medulloblastoma is driven by proteins deep within the cancer cells, for which there are often no effective drugs available. Researchers at Uppsala University have identified a new genetic technique that enables targeting of tumour cells with elevated levels of such proteins. The technique could be used to eliminate cells responsible for tumour relapse.
Some common hormonal contraceptives are linked to a slightly higher risk of breast cancer than others. This is shown by a new Swedish study from Uppsala University, in which researchers followed more than two million women and teenage girls in Sweden to identify how different hormonal contraceptives affect the risk of breast cancer.
Pregnant women with vitamin D deficiency may develop osteomalacia – a form of bone softening. A new Swedish study shows that this condition increases the risk of needing vacuum-assisted delivery or emergency caesarean section fivefold. Muscle weakness due to vitamin D and calcium deficiency may be a possible explanation, in addition to the pelvic changes historically associated with osteomalacia.
AI can be used to detect cervical cancer in women in resource-limited parts of the world. However, for this method to work, investments are needed in healthcare staff, reliable supply chains and trust in these communities.
More than 100,000 people are estimated to have died as a result of extreme heat during the summers of 2022 and 2023 in Europe. A new study shows that it is possible to make accurate forecasts of heat-related mortality about a week in advance. The forecasts could be used in heat warnings to protect vulnerable groups.
Fewer than one per cent of people who have changed their legal gender choose to revert to the gender they were assigned at birth. This has been shown in a new study from Uppsala University in which the researchers looked at how stable a gender change is over time in Sweden.
Men assessed as healthy after a pathologist analyses their tissue sample may still have an early form of prostate cancer. Using AI, researchers at Uppsala University have been able to find subtle tissue changes that allow the cancer to be detected long before it becomes visible to the human eye.
Parents of children diagnosed with type 1 diabetes suffer an income drop in the years following the diagnosis. The impact is more pronounced in mothers, especially mothers of children diagnosed in preschool years. These novel findings from a study led by researchers at Uppsala University, Sweden, have now been published in Diabetologia.
In the largest Nordic study to date concerning oesophageal cancer surgery, the researchers found clear evidence that decompression with a nasogastric tube is associated with less serious complications. Their results challenge a trend of declining use of the nasogastric tube after major surgical procedures.
An international research team led from Uppsala University has identified new mechanisms behind how the aggressive brain tumour glioblastoma spreads in the brain. Targeting the identified connection between the tumour invasion routes and the tumour cell states could be a potential new treatment strategy.
Most men who are treated for prostate cancer according to modern guidelines have good survival rates and the majority of these men will die of causes other than prostate cancer. This is revealed in a new study from Uppsala University published in the Journal of the National Comprehensive Cancer Network. "“We were surprised by how much life expectancy affected the prognosis" says Marcus Westerberg.
Targeted training interventions for both health professionals and parents significantly increase the amount of skin-to-skin contact between newborns and their parents in the first 48 hours after birth. The proportion of babies who received nearly 24 hours of skin contact over the first 24 hours increased from 33 per cent to 58 per cent. This is shown in a new study from Uppsala University.
How much an infant cries is largely steered by their genetics and there is probably not much that parents can do about it. This has been shown in a new Swedish twin study from Uppsala University and Karolinska Institutet in which researchers investigated how genetics and environment influence infants’ crying duration, sleep quality and ability to settle during the first months of life.
Giving birth to a child after 40 is becoming more and more common – but it can entail an increased risk to the child. A new study based on data from over 300,000 births in Sweden shows that children of older mothers are more often born prematurely or with complications, especially when the mother is 45 years of age or older.
In large parts of the world, women are having children later and later
With the aid of a 3D printer, researchers at Uppsala University have succeeded in creating a model that resembles human nerve tissue. The model, which can be cultured from the patient’s own cells, makes it possible to test new drug treatments in a lab environment.
Researchers at Uppsala University are questioning the gender-equality paradox. They show that it is not possible to draw the conclusions that women and men in gender-equal countries differ more in their preferences than women and men in less equal countries, from the data studied. "The question is based on Western perspectives and conditions and cannot be applied to other countries"(publ in PNAS)
Thanks to lab-grown miniature intestines, researchers at Uppsala University have successfully mapped how aggressive Shigella bacteria infect the human gut. The study opens the door to using cultured human mini-organs to investigate a wide range of other serious infections.
Researchers from Uppsala Antibiotic Center, Uppsala University and SciLifeLab describe a fundamental mechanism of antibiotic resistance. What happens in a bacterium that is resistant to the antibiotic fusidic acid? With a stop-motion movie at the atomic level, they can show that the resistance protein FusB works nearly like a crowbar. Article published in Nature Communications
