How bullying and obesity can affect girls’ and boys’ mental health
Depressive symptoms are more common in teenage girls than in their male peers. However, boys’ mental health appears to be affected more if they suffer from obesity. Irrespective of gender, bullying is a considerably greater risk factor than overweight for developing depressive symptoms. These conclusions are drawn by researchers at Uppsala University who monitored adolescents in a new study.
Conspiracy theories characterise views in and about Europe
Conspiratorial narratives of internal disintegration and external threats affect views in the European Union and Europe to an increasing extent. Our trust in society is put to the test in crises when various groups are singled out as the villains. In extreme cases, this can inspire acts of terror. Researchers from Uppsala University are among those demonstrating this in a new book.
Molecular biologists travel back in time 3 billion years
A research group working at Uppsala University has succeeded in studying ‘translation factors’ – important components of a cell’s protein synthesis machinery – that are several billion years old. By studying these ancient ‘resurrected’ factors, the researchers were able to establish that they had much broader specificities than their present-day, more specialised counterparts.
Socioeconomic deprivation modifies genetic influence on higher education
A comprehensive study from Uppsala University demonstrates that socioeconomic deprivation modifies genetic effects on higher education and abstract reasoning. The paper illustrates how genes play a greater role in educational attainment in more socioeconomically deprived regions of the United Kingdom. The study was recently published in the American Journal of Psychiatry.
Newly discovered immune cell function vital to healing
Researchers at Uppsala University have now discovered that one of the most common immune cells in the human body, macrophages, play an important role in re-establishing and controlling blood flow, something that can be used to develop new drugs.
David D. Laitin is awarded the Johan Skytte Prize in Political Science
David D. Laitin, Stanford University, is this year’s recipient of the Johan Skytte Prize, known by many as the ‘Nobel Prize in Political Science’. Professor Laitin is awarded the prize for his “original and objective explanation of how politics shapes cultural strategies in heterogeneous societies.”
Gut epithelium muscles up against infection
To maximise absorption of nutrients from the diet, the intestinal mucous membrane has a large surface area. However, this also makes it vulnerable to attack from aggressive gut microbes. A new study by Uppsala University researchers now shows that the surface layer of the mucosa, known as the epithelium, can rapidly contract when it recognises a bacterial attack.
Genome sequencing reveals a new species of bumblebee
While studying genetic diversity in bumblebees in the Rocky Mountains, USA, researchers from Uppsala University discovered a new species. They named it Bombus incognitus and present their findings in the journal Molecular Biology and Evolution.
New model can predict how bacteria develop antibiotic resistance
Using theoretical models of bacterial metabolism and reproduction, scientists can predict the type of resistance that bacteria will develop when they are exposed to antibiotics. This has now been shown by an Uppsala University research team, in collaboration with colleagues in Cologne, Germany. The study is published in the journal Nature Ecology and Evolution.
New light shed on the early evolution of limb bone marrow
When and how bone marrow first originated in the limbs of early four-legged animals is disputed in evolutionary biology. With the help of powerful X-ray technology, an international research team, led by Uppsala University, has now discovered that this evolutionary adaptation most likely took place after the first tetrapods stepped ashore. The study is published in the scientific journal eLife.
Sound-frequency map for inner ear created with advanced X-ray technology
Researchers at Uppsala University have created the first 3D map of the hearing nerve showing where the various sound frequencies are captured. Using what is known as synchrotron X-ray imaging, they were able to trace the fine nerve threads and the vibrating auditory organ, the cochlea, and find out exactly how the frequencies of incoming sound are distributed.
Beta blockers can repair malformed blood vessels in the brain
Propranolol, a drug that is efficacious against infantile haemangiomas (“strawberry naevi”, resembling birthmarks), can also be used to treat cerebral cavernous malformations, a condition characterised by misshapen blood vessels in the brain and elsewhere. This has been shown by researchers at Uppsala University in a new study published in the scientific journal Stroke.
Innate immune system worsens the situation in severe COVID-19
In patients with severe COVID-19, the innate immune system overreacts. This overreaction may underlie the formation of blood clots (thrombi) and deterioration in oxygen saturation that affect the patients. This is shown in an Uppsala University study published in the journal Frontiers in Immunology.
Metabolic response behind reduced cancer cell growth
Researchers from Uppsala University show in a new study that inhibition of the protein EZH2 can reduce the growth of cancer cells in the blood cancer multiple myeloma. The reduction is caused by changes in the cancer cells’ metabolism. These changes can be used as markers to discriminate whether a patient would respond to treatment by EZH2 inhibition.
Producing more sustainable hydrogen with composite polymer dots
Hydrogen for energy use can be extracted in an environmentally friendly way from water and sunlight, using photocatalytic composite polymer nanoparticles developed by researchers at Uppsala University. In laboratory tests, these “polymer dots” showed promising performance and stability alike. The study has been published in the Journal of the American Chemical Society.
New improved dog reference genome will aid a new generation of investigation
Researchers at Uppsala University and the Swedish University of Agricultural Sciences have used new methods for DNA sequencing and annotation to build a new, and more complete, dog reference genome. This tool will serve as the foundation for a new era of research, helping scientists to better understand the link between DNA and disease, in dogs and in their human friends.
Higher blood pressure at night than in daytime may increase Alzheimer’s disease risk
Higher blood pressure at night than in daytime may be a risk factor for Alzheimer's disease in older men. This is suggested by a new study from researchers at Uppsala University, now published in the journal Hypertension.
Warmer climate may make new mutations more harmful
A warmer global climate can cause mutations to have more severe consequences for the health of organisms through their detrimental effect on protein function. This may have major repercussions on organisms’ ability to adapt to, and survive in, the altered habitats of the future. This is shown in a new Uppsala University research study.
Faulty metabolism of Parkinson’s medication in the brain linked to severe side effects
Until now, the reason why the drug levodopa (L-Dopa), which reduces the motor symptoms of Parkinson’s disease, declines in efficacy after a few years’ use has been unknown. A side effect that then often occur is involuntary movements. A Swedish–French collaboration, led from Uppsala University, has now been able to connect the problems with defective metabolism of L-Dopa in the brain.
Parlour games 400 years ago – almost like today
In a new thesis from Uppsala University, art historian Greger Sundin studied 16th and 17th century games that have been preserved in princely collections for example. Right at the end of his work on the thesis, he and a colleague were able to solve an over 300 year old riddle about a game in the Augsburg Art Cabinet.