Sigrid Therapeutics today announced the publication of the SHINE clinical trial in eClinicalMedicine, part of The Lancet Discovery Science portfolio. The publication marks a major scientific milestone for the company, strengthening the foundation of its proprietary SiPore® technology platform and supporting the next phase of regulatory, clinical and commercial development.
SIGRID Therapeutics launches Carb Fence™, a new gut-local medical food designed to reduce the negative impact of modern meals. Powered by patented SiPore® technology, Carb Fence™ helps support steadier energy, fewer cravings, and lower post-meal glucose spikes by slowing digestion locally in the gut, offering a practical new approach to metabolic health in everyday life.
SIGRID Therapeutics announces the U.S. launch of Carb Fence™, its flagship medical food powered by patented SiPore® technology. The launch brings the clinically evaluated 9 g daily SiPore® dose to market for the first time, marking a major commercialization milestone following more than 15 years of research and multiple clinical studies.
Modern meals are easy to eat — and easy to absorb quickly.
That often leads to a familiar pattern:You eat, feel fine at first, and then a few hours later feel tired, hungry, or start craving something sweet.
This is not just about willpower.It’s about how quickly energy enters your system.
SiPore® is designed to act at that exact moment — during digestion.
How SiPore® works
1. Taken
Post highlights: -What “metabolically healthy” really means -Why metabolic health affects energy, appetite, and long-term wellbeing -How modern meals can place stress on metabolism -Signs of healthy metabolic function -Simple habits that support metabolic health -How supporting steadier post-meal responses may help maintain metabolic balance
Modern food is designed for speed, taste, and convenience. It is not designed around how the body processes energy. Many meals today are rich in carbohydrates and fats that are broken down and absorbed very quickly. When energy enters the system rapidly, it can lead to sharp rises after eating followed by dips later on.
Those dips are familiar to many people. You eat lunch, feel fine at f
Sigrid Therapeutics (Sigrid), a science-driven consumer health company developing innovative solutions for metabolic health, today announced the appointment of Claus Kjaersgaard as its new Chief Executive Officer. Claus will assume the role on 1 February 2026.
